Peptides and Neurological Disease

Edited by

  • P.C. Emson
  • M. Rossor
  • M. Tohyama

This excellent review volume includes a comprehensive selection of provocative articles from pioneering authorities on the role that peptides play in key neurological diseases. The book, after an introductory chapter on immunohistochemical techniques, reviews neurological conditions in three sections according to anatomical distinction: basal ganglia, cerebral cortex, and spinal cord and the PNS. The volume closes with an inspiring section on therapeutic perspectives. The broad scope of this volume will appeal to all neuroscientists, neurologists and psychiatrists engaged in unravelling complex neurological disorders.
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Book information

  • Published: January 1986
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-80733-5

Table of Contents

Part I: Introduction. Chapter 1. Introduction and Historical Perspective. 2. Immunohistochemical Techniques (S. Shiosaka and M. Toyama). Part II: Basal Ganglia. 3. Distribution of Peptides in Basal Ganglia (H. Takagi). 4. Physiology of Peptides in Basal Ganglia (S. Hosokawa and M. Kato). 5. Peptides in Huntington's Disease (P. Emson et al.). 6. Neuropeptides and Parkinson's Disease (Y. Agid et al.). Part III: Cerebral Cortex. 7. Morphology and Distribution of Peptide-containing Neurons in Cerebral Cortex (J. Parnavelas). 8. Cerebral changes in Alzheimer's Disease (F. Plum). 9. Peptide changes in Dementia (M. Rossor et al.). 10. Neuropeptides in Schizophrenia (G. Bissette et al.). Part IV: Spinal Cord and Peripheral Nervous System. 11. Neuropeptides in Spinal Cord (M. Tohyama and Y. Shiotani). 12. Neurochemistry and Neural Circuitry in the Dorsal Horn (M. Ruda, G. Bennett and R. Dubner). 13. Peptides in the Peripheral Nervous System (S. Inagaki and S. Kito). 14. Peptides in Body Fluids in Pain (S. Capper). Part V: Therapeutic Perspectives. 15. The Design of Antagonists of Regulatory Peptides (Morley). 16. Studies on Peptide Comodulator Transmission New Perspectives on the Treatment of Disorders of C.N.S. (K. Fuxe et al.). 17. Clinical Relevance of Neuropeptide Research (C.D. Marsden).