Peptide Solvation and H-bonds book cover

Peptide Solvation and H-bonds

Volume 72 addresses the role of peptide backbone solvation in the energetics of protein folding. Particular attention is focused on modeling and computation. This volume will be of particular interest to biophysicists and structural biologists.

Audience
Biochemists, biophysicists, cell biologists, protein chemists, and structural biologists

Hardbound, 312 Pages

Published: March 2006

Imprint: Academic Press

ISBN: 978-0-12-034272-3

Reviews

  • PRAISE FOR THE SERIES: "The authority, originality, and editing of the reviews are first class." -NATURE "The Advances in Protein Chemistry series has been a major factor in the education of protein chemists." -JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Contents

  • Preface: New Directions in the Study of Peptide H-bonds and Peptide Solvation1. Potential Functions for Hydrogen Bonds in Protein Structure Prediction and Design2. Backbone-Backbone H-Bonds Make Context Dependent Contributions to Protein Folding Kinetics and Thermodynamics: Lessons from Amide-to-Ester Mutations3. Modeling Polarization in Proteins and Protein-Ligand Complexes: Methods and Preliminary Results4. Hydrogen Bonds in Molecular Mechanics Force Fields5. Resonance Character of Hydrogen-Bonding Interactions in Water and Other H-Bonded Species6. How Hydrogen Bonds Shape Membrane Protein Structure7. Peptide and Protein Folding and Conformational Equilibria: Theoretical Treatment of Electrostatics and Hydrogen Bonding with Implicit Solvent Models8. Thermodynamics of alpha-Helix Formation9. The Importance of Cooperative Interactions and A Solid State Paradigm to Proteins – What Peptide Chemists Can Learn from Molecular Crystals

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