Pediatric Critical Care book cover

Pediatric Critical Care

Now completely revised and updated, this definitive, easy-to-use text guides you through all aspects of caring for the critically ill child. The clear, logical organ-system approach addresses development, function, disease, and treatment for a full range of disease entities. This new edition includes chapters covering hemodynamic principles, diagnostic and therapeutic cardiac catheterization, congenital malformations of brain and spinal chord, and gastrointestinal pharmacology. A completely new section has been added that considers the failure of organ systems. Multidisciplinary in approach, the book addresses pharmacology, nursing, administration, ethics, and other areas of concern to the whole pediatric ICU team.

Critical Care Specialists, Pediatricians, Pediatric Residents, Anesthesiologists, Anesthesiology Residents, Nurse Anesthetists, Health Science Libraries


Published: December 2005

Imprint: Mosby

ISBN: 978-0-323-01808-1


  • I. The Discipline

    1. Multidisciplinary Critical Care and the Role of the Pediatric Subspecialist in the PICU
    2. History of Pediatric Intensive Care
    3. Pediatric Critical Care and the Intensivist in the New Hospital Environment
    4. The Nurse in Pediatric Critical Care
    5. Research in Pediatric Critical Care
    6. Proving the Point: Evidence-Based Medicine in Pediatric Critical Care
    7. Outcome Prediction in Pediatric Critical Care
    8. Safety and Quality Assessment in the PICU
    9. Information Technology in Critical Care
    10. Family-Centered Care in the PICU
    11. Ethics in Pediatric Intensive Care
    12. Ethical Issues in Death and Dying
    13. Pediatric Transplantation and Organ Donation
    14. Pediatric Transport: Shifting the Paradigm to Improve Patient Outcome
    15. Pediatric Vascular Access and Centeses
    16. Pediatric Intensive Care in Developing Countries

    Section: II. Organ System Function and Failure

    A. Circulation

    17. Structure and Function of the Heart
    18. Regional Circulation
    19. Principles of Invasive Monitoring
    20. Assessment of Cardiovascular Function
    21. Echocardiography and Noninvasive Cardiac Diagnosis
    22. Diagnostic and Therapeutic Cardiac Catheterization
    23. Pharmacology of the Cardiovascular System
    24. Cardiopulmonary Interactions
    25. Myocardial Dysfunction, Extracorporeal Membrane Oxygenation, and Ventricular Assist Devices
    26. Disorders of Cardiac Rhythm
    27. Shock States
    28. Cardiac Bypass for Repair of Congenital Heart Disease in Infants and Children
    29. Cardiac Intensive Care
    30. Cardiac Transplantation

    Section: II. Organ System Function and Failure

    B. Respiration

    31. Structure of the Respiratory System
    32. Pediatric Airway Management
    33. Physiology of the Respiratory System
    34. Control of Breathing and Acute Respiratory Failure
    35. Assessment and Monitoring of Respiratory Function
    36. Ventilation/Perfusion Mismatch
    37. Mechanical Dysfunction of the Respiratory System
    38. Noninvasive Monitoring in Children
    39. Specific Diseases of the Respiratory System: Upper Airway
    40. Asthma
    41. Neonatal Respiratory Disease
    42. Pneumonitis and Interstitial Disease
    43. Diseases of Pulmonary Circulation
    44. Mechanical Ventilation and Respiratory Care
    45. Ventilator-Induced Lung Injury
    46. Acute Respiratory Distress Syndrome in Children
    47. Extracorporeal Life Support

    Section: II. Organ System Function and Failure

    C. CNS and Neuromuscular

    48. Development, Structure, and Function of the Brain and Neuromuscular Systems
    49. Neuroimaging
    50. Pediatric Neurologic Assessment and Monitoring
    51. Congenital Malformations of the Brain and Spinal Cord
    52. Intracranial Hypertension and Brain Monitoring
    53. Postoperative Neurosurgical Intensive Care
    54. Coma and Depressed Sensorium
    55. Status Epilepticus
    56. Acute Neuromuscular Diseases and Disorders in Pediatric Critical Care
    57. Acute Central Nervous System Infections
    58. Hypoxic-Ischemic Encephalopathy: Pathobiology and Therapy of the Postresuscitation Syndrome in Children

    Section: II. Organ System Function and Failure

    D. Renal

    59. Renal Structure and Function
    60. Electrolyte Management in Pediatric Critical Illness
    61. Acid-Base Disorders
    62. Tests of Renal Function
    63. Renal Pharmacology
    64. Glomerulotubular Dysfunction and Acute Renal Failure
    65. Pediatric Renal Replacement Therapy in the Intensive Care Unit

    Section: II. Organ System Function and Failure

    E. Metabolism and Endocrine

    66. Hypertension in the PICU
    67. Cellular Bioenergetic Pathways and Processes
    68. Nutrition in the Critically Ill Child
    69. Inborn Errors of Metabolism
    70. Disorders of the Endocrine System and Pediatric Critical Illness
    71. Diabetic Ketoacidosis

    Section: II. Organ System Function and Failure

    F. Hematology

    72. Structure and Function of Hematopoietic Organs
    73. Thromboembolism in Pediatric Critical Care Patients
    74. Hematology and Oncology Problems in the Intensive Care Unit
    75. Basics of Transfusion Medicine
    76. Hematopoietic Stem Cell Transplantation
    77. Hemaglobinopathy

    Section: II. Organ System Function and Failure

    G. Gastroenterology

    78. Gastrointestinal Structure and Function
    79. Disorders and Diseases of the Gastrointestinal Tract and Liver
    80. Gastrointestinal Pharmacology
    81. Acute Liver Failure, Liver Transplantation, and Extracorporeal Liver Support
    82. Acute Abdomen

    Section: II. Organ System Function and Failure

    H. Immunity and Infection

    83. The Innate Immune System
    84. Infection and the Host Response
    85. Congenital Immunodeficiency
    86. Acquired Immune Dysfunction
    87. Bacterial Infection, Antimicrobial Use and Resistant Organisms in the PICU
    88. Life-Threatening Viral Disease and Its Treatment
    89. Infectious Syndromes in the PICU
    90. Nosocomial Infection in the PICU
    91. Rheumatic Diseases and Their Treatment
    92. Genomic and Proteomic Medicine in Critical Care

    Section: II. Organ System Function and Failure

    I. Failure of Organ Systems

    93. Molecular Foundations of Cellular Injury: Apoptosis and Necrosis
    94. Endotheliopathy
    95. Neuroendocrine-Immune Mediator Coordination and Disarray in Critical Illness
    96. Sepsis
    97. Pediatric Multiple Organ Dysfuncation Syndrome

    Section: III. Environmental Hazards

    98. Principles of Toxin Screening, Assessment and Detoxification
    99. Toxidromes and Their Treatment
    100. Bites and Stinges
    101. Heat Injury
    102. Cold Injury
    103. Near-Drowning
    104. Burn and Inhalation Injuries

    Section: IV. Trauma

    105. Evaluation, Stabilization and Initial Management After Multiple Trauma
    106. Child Abuse and Neglect
    107. Severe Traumatic Brain Injury in Infants and Children
    108. Thoracic Injuries in Children
    109. Abdominal Trauma in Pediatric Critical Care

    V. Pharmacology

    110. Principles of Drug Disposition in the Critically Ill Child
    111. Molecular Aspects of Drug Actions: from Receptors to Effectors
    112. Adverse Drug Reactions and Drug-Drug Interactions

    VI. Anesthesia and Analgesia Aspects of Pediatric Critical Care

    113. Organ System Considerations that Affect Anesthetic Management
    114. Anesthetic Principles and Operating Room Anesthesia Regimens
    115. Neuromuscular Blocking Agents
    116. Sedation and Analgesia
    117. Malignant Hyperthermia

    VII. Cardiopulmonary Resuscitation

    118. Physiologic Foundations of Cardiopulmonary Resuscitation
    119. Pediatric Cardiopulmonary Resuscitation



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