Patterning and Cell Type Specification in the Developing CNS and PNS

Comprehensive Developmental Neuroscience

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems.
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Neurosciencentists (developmental and translational) and developmental biology researchers


Book information

  • Published: May 2013
  • ISBN: 978-0-12-397265-1


"This first volume of the Comprehensive Developmental Neuroscience series, presented by editors Rubenstein and Rakic, draws from developmental biology, cell biology, molecular genetics, and nervous system morphology to give a rounded picture of the course of neurological developmentā€¦ Intended to be useful for researchers, clinicians, and students, the text is extensive with references to primary research and contains many full-color illustrations."--Reference & Research Book News, October 2013

Table of Contents

Brain Development: Normal Mechanisms and Disease Mechanisms

Preliminary structure - details to be confirmed in planning meeting. Section editor candidates in brackets (* with those that have been talked to already)

1. Section 1 - Principles (Chris Doe, Luis Puelles)
2. Section: Generation of Cell Types (David Anderson, Francois Guillemot, Tom Jessell, Chris Doe)
3. Section: Migration (Joe Gleensen, LW Tsai, Oscar Marin, Chris Walsh)
4. Section: Formation of Axons and Dendrites (Marc Tessier-Lavigne, F. Polleux, YN Jan)
5. Section: Synaptogenesis (Jeff Lichtman, Josh Sanes)
6. Section: Differentiation of Electrical Properties (Y Ben-Ari, Roger Nicol)
7. Section: Glia, Bloodvessels, Choroid Plexus, Immune Cells (Ben Barres)
8. Section: Circuit Development (Takao Hensch, Michael Styker, Carla Shatz)
9. Section: Cognitive Development (Adele Diamond, Torkel Klingberg, Tomas Paus)
10. Section: Cell Cycle (tbd)
11. Section: Cell Death (tbd)