Pathophysiology

The Biologic Basis for Disease in Adults and Children

By

  • Kathryn McCance, RN, PhD, Professor, College of Nursing, University of Utah, Salt Lake City, UT
  • Sue Huether, RN, PhD, Professor Emeritus, College of Nursing, University of Utah, Salt Lake City, UT

With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 7th Edition helps you understand the most important and the most complex pathophysiology concepts. More than 1,200 full-color illustrations and photographs make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a NEW Epigenetics and Disease chapter along with additional What’s New boxes highlighting the latest advances in pathophysiology. Written by well-known educators Kathryn McCance and Sue Huether, and joined by a team of expert contributors, this resource is the most comprehensive and authoritative pathophysiology text available!
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Book information

  • Published: January 2014
  • Imprint: MOSBY
  • ISBN: 978-0-323-08854-1


Table of Contents

PART ONE: CENTRAL CONCEPTS OF PATHOPHYSIOLOGY: CELLS AND TISSUES
Unit I: The Cell
1. Cellular Biology
2. Altered Cellular and Tissue Biology
3. The Cellular Environment: Fluids and Electrolytes, Acids and Bases
Unit II: Genes and Gene-Environment Interaction
4. Genes and Genetic Diseases
5. Genes, Environment-Lifestyle, and Common Diseases
6. Epigenetics and Disease  NEW!
Unit III: Mechanisms of Self-Defense
7. Innate Immunity: Inflammation
8. Adaptive Immunity
9. Alterations in Immunity and Inflammation
10. Infection
11. Stress and Disease
Unit IV: Cellular Proliferation: Cancer
12. Cancer Biology
13. Cancer Epidemiology
14. Cancer in Children
PART TWO: PATHOPHYSIOLOGIC ALTERATIONS: ORGANS AND SYSTEMS
Unit V: The Neurologic System
15. Structure and Function of the Neurologic System
16. Pain, Temperature Regulation, Sleep, and Sensory Function
17. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function
18. Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
19. Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders
20. Alterations of Neurologic Function in Children
Unit VI: The Endocrine System
21. Mechanisms of Hormonal Regulation
22. Alterations of Hormonal Regulation
Unit VII: The Reproductive Systems
23. Structure and Function of the Reproductive Systems
24. Alterations of the Female Reproductive System
25. Alterations of the Male Reproductive System
26. Sexually Transmitted Infections
Unit VIII: The Hematologic System
27. Structure and Function of the Hematologic System
28. Alterations of Erythrocyte Function
29. Alterations of Leukocyte, Lymphoid, and Hemostatic Function
30. Alterations of Hematologic Function in Children
Unit IX: The Cardiovascular and Lymphatic Systems
31. Structure and Function of the Cardiovascular and Lymphatic Systems
32. Alterations of Cardiovascular Function
33. Alterations of Cardiovascular Function in Children
Unit X: The Pulmonary System
34. Structure and Function of the Pulmonary System
35. Alterations of Pulmonary Function
36. Alterations of Pulmonary Function in Children
Unit XI: The Renal and Urologic Systems
37. Structure and Function of the Renal and Urologic Systems
38. Alterations of Renal and Urinary Tract Function
39. Alterations of Renal and Urinary Tract Function in Children
Unit XII: The Digestive System
40. Structure and Function of the Digestive System
41. Alterations of Digestive Function
42. Alterations of Digestive Function in Children
Unit XIII: The Musculoskeletal System
43. Structure and Function of the Musculoskeletal System
44. Alterations of Musculoskeletal Function
45. Alterations of Musculoskeletal Function in Children
Unit XIV: The Integumentary System
46. Structure, Function, and Disorders of the Integument
47. Alterations of the Integument in Children
Unit XV: Multiple Interacting Systems
48. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults
49. Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children