Osteoarthritis book cover


A Companion to Rheumatology

This new companion to Hochberg et al.'s Rheumatology masterwork presents current insights into the causes, detection, and therapy of this condition. It provides "one-stop" coverage of scientific and clinical developments, including new concepts in epidemiology and genetics and pathogenic mechanisms · new developments in diagnostic interventions and prevention · and the very latest concepts in treatment.

Rheumatologists, Physiatrists and Internists

Hardbound, 296 Pages

Published: May 2007

Imprint: Mosby

ISBN: 978-0-323-03929-1



    1. Epidemiology of OA


    2. Role of bone in OA

    3. Impact of Mechanical Stress on the Pathophysiology of OA

    4. Update on the Chondrocyte Lineage and Implication for Cell Therapy in OA

    5. Aging Cartilage and OA Cartilage: Differences and Shared Mechanisms

    6. Role of Adipocytokines in OA

    7. Novel Experimental Models for the Study of OA

    8. Signaling Transduction: Targets in OA


    9. Biomarkers, Evidence for Promising Markers

    10. Update on Radiographic Imaging

    11. Update on MRI in OA


    12. Update on COX-2 Inhibitors, Non-selective NSAIDs, and ASA Co-therapy

    13. Alternative Therapies in OA

    14. Novel Physical Therapy Approaches to Enhance Muscle Activity and Minimize Instability in OA

    15. Disease-Modifying Drugs in OA

    16. Nutritional Supplements in the Treatment of OA


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