Origin and Evolution of Viruses
- Esteban Domingo, Centro de Biologia Molecular Severo Ochoa, Madrid, Spain
- Colin Parrish, Cornell University, Ithaca, NY, USA
- John Holland, University of California, San Diego, La Jolla, USA
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases.
Animal and plant virologists working in research and teaching. Evolutionary biologists and ecologists. Experts in public health, disease surveillance and zoonotic viral disease.