Origin and Evolution of Viruses

Edited by

  • Esteban Domingo, Centro de Biologia Molecular Severo Ochoa, Madrid, Spain
  • Colin Parrish, Cornell University, Ithaca, NY, USA
  • John Holland, University of California, San Diego, La Jolla, USA

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases.
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Animal and plant virologists working in research and teaching. Evolutionary biologists and ecologists. Experts in public health, disease surveillance and zoonotic viral disease.


Book information

  • Published: June 2008
  • ISBN: 978-0-12-374153-0


Review of the previous edition: "...this book...is a detailed account of current thinking on virus evolution... Because of the diversity of subjects, this book gives an up to date picture of research in various fields of virology, and helps to tease out connections between these fields. The subjects covered are essential reading for virologists but also have direct relevance for molecular biologists, and indeed any researchers with interests in early evolution... This publication is highly recommended for its breadth of coverage and detailed treatments of the various subjects"--TODAY'S LIFE SCIENCE (February 2001)

Table of Contents

1. Early Replication: Origin and EvolutionPeter Schuster and Peter F. Stadler2. Structure and Evolution of ViroidsNúria Duran-Vila, Santiago F. Elena, José-Antonio Daròs and Richard Flores3. Mutation, Competition and Selection as Measured with Small RNA MoleculesChristof K. Biebricher4. Viral Quasispecies: Dynamics, Interactions and PathogenesisEsteban Domingo, Cristina Escarmís, Luis Menéndez-Arias, Celia Perales, Mónica Herrera, Isabel S. Novella and John J. Holland5. Comparative Studies of RNA Virus EvolutionEdward C. Holmes6. Nucleic Acid Polymerase Fidelity and Viral Population FitnessEric Smidansky, Jamie J. Arnold and Craig E. Cameron7. The complex Interactions of Viruses and the RNAi Machinery: A Driving Force in Viral EvolutionRonald P. van Rij and Raul Andino8. The Role of the APOBEC3 Family of Cytidine Deaminases in Innate Immunity, G-to-A Hypermutation, and Evolution of RetrovirusesMarie L. Santiago and Warner C. Greene9. Lethal MutagenesisJ.J. Bull and C.O. Wilke10. Evolution of dsDNA Tailed PhagesRoger W. Hendrix11. More about Plant Virus Evolution – Past, Present and FutureAdrian Gibbs, Mark Gibbs, Kazusato Ohshima and Fernando García-Arenal12. Mutant clouds and bottleneck events in plant virus evolutionMarilyn J. Roossinck13. Retrovirus EvolutionSimon Wain-Hobson14. Intra-host dynamics and evolution of HIV InfectionViktor Müller and Sebastian Bonhoeffer15. The Impact of Rapid Evolution of Hepatitis VirusesJ. Quer, M. Martell, F. Rodriguez, A. Bosch, R. Jardi, M. Buti and J.I. Esteban16. Arbovirus EvolutionKathryn A. Hanley and Scott C. Weaver17. Evolution and Variation of the ParvovirusesKarin Hoelzer and Colin R. Parrish18. Genome Diversity and Evolution of PapillomavirusesHans-Ulrich Bernard19. Origin and Evolution of PoxvirusesJohn W. Barrett and Grant McFadden20. Molecular Evolution of the HerpesviralesDuncan J.McGeoch, Andrew J. Davison, Aidan Dolan, Derek Gatherer and Edgar E. Sevilla-Reyes21. The widespread evolutional significance of virusesLuis P. Vollareal