Optical Coherence Tomography book cover

Optical Coherence Tomography

Principles and Practice

OCT is a medical high-resolution imaging technology that offers several distinct advantages over current medical imaging technologies. With a resolution 25x greater than current technologies, its ability to be engineered very small due to its fiber-based design, and it is high speed with frame rates close to video rates, this technology is attracting many researchers.

This second edition brings together information needed by the various, and sometimes disparate, groups using and studying this technology. It is completely updated throughout with the most recent research and applications. This is not a book on how to build OCT devices, but rather gives a broad treatment of the subject including 1) the optics, science, and physics needed to understand the technology; 2) a description of applications with a critical look at how the technology will successfully address actual clinical need; and 3) a discussion of delivery of OCT to the patient, FDA approval and comparisons with available competing technologies.

While the required mathematical rigor is present where needed, it is presented in such a way that non-scientists and non-engineers will be able to gain a basic understanding of OCT its applications, as well as the issues of bringing the technology to the market.

Optical engineers; biomedical and clinical scientists; clinicians; medical doctors; researchers; manufacturers of OCT devices.

Hardbound, 650 Pages

Published: August 2015

Imprint: Elsevier

ISBN: 978-0-12-396964-4


  • Foreword

    Section I:

    Chapter 1. The Basics (math, waves, etc.) for the Nonphysical Scientist

    Chapter 2. Light and Electromagnetic Waves

    Chapter 3. Light in Matter

    Chapter 4. Interference, Coherence, Diffraction, and Transfer Functions

    Section II:

    Chapter 5. Optical Coherence Tomography Theory

    Chapter 6. Optoelectronics And Optical Components

    Chapter 7. Noise and System Performance with TD-OCT and SD-OCT

    Chapter 8. Polarization and Polarization Sensitive OCT (PS-OCT)

    Chapter 9. Adjuvant Techniques: Absorption Spectroscopy, Contrast Probes, Phase Contrast, Elastography, and Entangled Photons

    Chapter 10. Doppler Optical Coherence Tomography

    Chapter 11. Digital Image Processing Techniques for Speckle Reduction, Enhancement and Segmentation of Optical Coherence Tomography (OCT) Images

    Section III

    Chapter 12. Application of OCT to Clinical Imaging: Introduction

    Chapter 13. Other Technologies

    Chapter 14. Introduction to Clinical Research Design and Analysis

    Chapter 15. OCT in Cardiovascular Medicine

    Chapter 16. OCT in Musculoskeletal Disease

    Chapter 17. OCT in Oncology

    Chapter 18. Other Applications and Conclusions


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