One and Two Dimensional NMR Spectroscopy


  • A.U. Rahman, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan

The field of nuclear magnetic resonance spectroscopy has undergone explosive development during the last decade with the advent of new one- and two-dimensional techniques. The author has had extensive experience in the use of these techniques for the structure elucidation of complex natural products, and in this book he gives a comprehensive, up-to-date and very readable account of these developments.

The book's scope is very wide. It starts from fundamental principles of modern NMR spectroscopy, describing the instrumentation and its optimum use, and extends to the latest developments such as inverse measurements. Emphasis is on problem-solving so as to be useful to a large number of organic chemists, biochemists and medicinal chemists. The problems and worked solutions at the end of the chapters will help students to gain proficiency in the application of these new techniques. Those who are learning how to operate modern NMR spectrometers will find particularly useful the description of such basic aspects as shimming, probe tuning, and methods for improvement of resolution and sensitivity.

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Book information

  • Published: April 1989
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-87316-3


A valuable practical guide to the structural elucidation of organic compounds.
Journal of Organometallic Chemistry

Atta-ur-Rahman succeeds in conveying the scope and power of one- and two-dimensional NMR and shows clearly how structural information can be extracted.

Table of Contents

Foreword (Lloyd M. Jackman). 1. Basic Principles of Modern NMR Spectroscopy. 2. Spin-Echo and Polarisation Transfer. 3. Carbon-Carbon Connectivity - 1D Inadequate Spectra. 4. The Nuclear Overhauser Effect. 5. Two-Dimensional NMR Spectroscopy - Basic Principles. 6. Heteronuclear 2D J-Resolved Spectroscopy. 7. Homonuclear 2D J-Resolved Spectroscopy. 8. Homonuclear 2D Shift Correlated Spectroscopy. 9. Chemical Shift Correlation Through Cross-Relaxation and Exchange. 10. Heteronuclear 2D-Shift Correlation Spectroscopy. 11. Cross Polarisation in the Rotating Frame. 12. 2D Multiple-Quantum Spectroscopy. 13. Tackling the Structure. 14. Product Operator Approach to 2D-NMR Spectroscopy. Appendix 1. Some Terms, Symbols and Acronyms used in NMR Spectroscopy. Appendix 2. Summary of Important 2D NMR Techniques. Index.