Omega-3 Fatty Acids in Brain and Neurological Health

Edited by

  • Ronald Watson, Professor of Health Promotion Sciences, Mel and Enid Zuckerman Arizona College of Public Health and School of Medicine, Tucson, AZ, USA
  • Fabien De Meester, Managing Director, DMF Ltd Co, Belgium

Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons.

Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis. This book encompasses some of the most recent research, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep, and neurodegenerative diseases. This collection helps to push research forward toward a complete understanding of omega-3 fatty acids' relationship to brain and neurological health.

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Neuroscience/neurology research, nutrition research


Book information

  • Published: June 2014
  • ISBN: 978-0-12-410527-0


"This unique encyclopedic work is a great resource for anyone interested in this ubiquitous and fascinating fatty acid. I highly recommend it. Score: 79 - 3 Stars",December 12,2014

Table of Contents

I: Overview of Neurological Changes: Targets for Dietary Omega-3 Fatty Acids
1. Enhanced longevity and role of omega-3 fatty acids; 2. Molecular gerontology: Principles and perspectives for interventions; 3. Peroxisomal pathways, their role in neurodegenerative disorders and therapeutic strategies; 4. Unregulated lipid preoxidation in neurological dysfunction; 5. Obesity, Western diet intake, and cognitive impairment; 6. Genetic risk factors for diabetic neuropathy; 7. n-3 fatty acid-derived lipid mediators against neurological oxidative stress and neuroinflammation; 8. The impact of omega-3 fatty acids on quality of life
II: Fatty Acids and Brain
9. Mammalian fatty acid amides of the brain and CNS; 10. Low omega-3 fatty acids diet and the impact on the development of visual connections and critical periods of plasticity; 11. The effects of omega-3 polyunsaturated fatty acids on maternal and child mental health; 12. Pain as modified by polyunsaturated fatty acids; 13. Fish oil supplementation prevents age-related memory decline: Involvement of nuclear hormone receptors; 14. Role of omega 3 fatty acids in brain and neurological health with special reference to clinical depression; 15. Omega 3 fatty acid supplementation for major depression with chronic disease; 16. The effectiveness of fish oil as a treatment for ADHD
17. Fatty acids and the aging brain; 18. Cerebrovascular changes: The role of fat and obesity; 19. The role of omega-3 fatty acids on Alzheimer's disease
III: Omega-3 Fatty Acids and Structural Changes in Neuronal Tissues
20. Substantia nigra modulation by essential fatty acids; 21. The role of omega-3 fatty acids in hippocampal neurogenesis; 22. Imaging brain DHA metabolism in vivo, in animals and humans
IV: Fatty Acids in Brain and Neurological Function in Infants and Children
23. Obesity and migraine in children; 24. Dietary omega-3 sources during pregnancy and the developing brain: Lessons from studies in rats
V: Fatty Acids and Neurological Outcomes
25. Omega-3 fatty acids and cognitive behavior; 26. Lipid and lipid signaling in Drosophila models of neurodegenerative diseases; 27. Polyunsaturated fatty acids in relation to sleep quality and depression in obstructive sleep apnea hypopnea syndrome; 28. Omega-3 fatty acids in intellectual disability, schizophrenia, depression, autism and attention-deficit hyperactivity disorders; 29. Effect of omega 3 fatty acids on aggression; 30. Multiple sclerosis: Modification of fish oil; 31. Deuterium protection of polyunsaturated fatty acids against lipid peroxidation: A novel approach to mitigating mitochondrial neurological diseases
VI: Dietary Fats, Obesity and Adverse Neurological Effects
32. Obesity, cognitive function and dementia: A life-span prospective; 33. Dairy products and cognitive functions; 34. Obesity and chronic low back pain: A kinematic approach; 35. Fatty acids and the hippocampus
VII: Contaminants and Removal from Fish Oils
36. Fish oil supplements, contaminants, excessive doses; 37. Introduction to fish oil oxidation, oxidation prevention and oxidation correction