Nunn's Applied Respiratory Physiology

Nunn's Applied Respiratory Physiology, Seventh Edition covers all aspects of respiratory physiology in health, disease, and altered conditions and environments, from basic science to clinical applications.

  • Includes functional anatomy, mechanics, control of breathing, ventilation, circulation, ventilation-perfusion matching, diffusion, carbon dioxide and oxygen, and non-respiratory functions of the lung.
  • Discusses the effects of pregnancy, exercise, sleep, altitude, pressure, drowning, smoking, anaesthesia, hypocapnia, hypercarbia, hypoxia, hyperoxia, and anaemia on respiratory physiology.
  • Explores specific clinical disorders such as ventilatory failure, airways disease, pulmonary vascular disease, parenchymal lung disease, and acute lung injury, as well as the physiological basis of current therapies, including artificial ventilation, extrapulmonary gas exchange, and lung transplantation.
  • Chapter on Parenchymal Lung Disease has been specifically expanded to include the physiology and pathology of the pleural space and lung cancer.
  • Contains a new chapter on Pulmonary Surgery, covering a wide range of surgical interventions  from bronchoscopy to lung resection.
  • Includes almost 500 new references to the literature.

The result is an invaluable source for those preparing for examinations in anaesthesia and intensive care, as well as an essential purchase for practitioners who want quick reference to current knowledge.

Trainee and practicing anaesthetists, intensivists, respiratory physicians and those seeking information on the basic principles and applications of lung function.


Published: September 2012

Imprint: Churchill Livingstone

ISBN: 978-0-7020-5416-7


  • Part 1 Basic Principles
    1 The Atmosphere
    2 Functional Anatomy of the Respiratory Tract
    3 Elastic Forces and Lung Volumes
    4 Respiratory System Resistance
    5 Control of Breathing
    6 Pulmonary Ventilation
    7 The Pulmonary Circulation
    8 Distribution of Pulmonary Ventilation and Perfusion
    9 Diffusion of Respiratory Gases
    10 Carbon Dioxide
    11 Oxygen
    12 Non-respiratory Functions of the Lung
    13 The History of Respiratory Physiology

    Part 2 Applied Physiology

    14 Pregnancy, Neonates and Children
    15 Exercise
    16 Sleep
    17 High Altitude and Flying
    18 High Pressure and Diving
    19 Respiration in Closed Environments and Space
    20 Drowning
    21 Smoking and Air Pollution
    22 Anaesthesia
    23 Changes in the Carbon Dioxide Partial Pressure
    24 Hypoxia
    25 Anaemia
    26 Hyperoxia and Oxygen Toxicity

    Part 3 Physiology of Pulmonary Disease

    27 Ventilatory Failure
    28 Airways Disease
    29 Pulmonary Vascular Disease
    30 Diseases of the Lung Parenchyma and Pleura
    31 Acute Lung Injury
    32 Respiratory Support and Artificial Ventilation
    33 Pulmonary Surgery

    Appendix A
    Physical quantities and units of measurement

    Appendix B
    The gas laws

    Appendix C
    Conversion factors for gas volumes

    Appendix D
    Symbols and abbreviations

    Appendix E
    Mathematical functions relevant to respiratory physiology


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