Nuclear Magnetic Resonance, Part A: Special Techniques and Dynamics
Volume 176: Nuclear Magnetic Resonance Part A
- Norman Oppenheimer, School of Pharmacy, University of California, San Francisco, U.S.A.
- Thomas James, School of Pharmacy, University of California, San Francisco, U.S.A.
- John Abelson, California Institute of Technology, Division of Biology, Pasadena, U.S.A.
- Melvin Simon, The Salk Institute, La Jolla, CA, USA
This volume, as does Volume 177, provides a general background of modern NMR techniques, with a specific focus on NMR techniques that pertain to proteins and enzymology, and a "snapshot" of the current state of the art in NMR experimental techniques. These books enable the reader to understand a given technique, to evaluate its strengths and limitations, to decide which is the best approach, and, finally, to design an experiment using the chosen technique to solve a problem.View full description
Biochemists, organic chemists, analytical chemists, biophysicists, physical chemists, and drug company researchers.
- Published: September 1989
- Imprint: ACADEMIC PRESS
- ISBN: 978-0-12-182077-0
"There is little doubt but that... this is a useful volume to have available at the lab bench."
Praise for the Volume, --FEBS LETTERS
"The editors have succeeded in producing a book that can serve as a very good source of information when one wishes to begin working in a new area... The individual chapters generally provide well-balanced, reliable, and up-to-date accounts of the techniques, with adequate references to the major basic papers. This is a good, readable book and a valuable reference volume."--ANALYTICAL BIOCHEMISTRY
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Table of ContentsBasic Techniques: J.A. Ferretti and G.H. Weiss, One-Dimensional Nuclear Overhauser Effects and Peak Intensity Measurements. J.L. Markley, Two-Dimensional Nuclear Magnetic Resonance Spectroscopy of Protein: An Overview. P.J. Hore, Solvent Suppression. N.J. Oppenheimer, Sample Preparation. Advanced Techniques: G. Wagner, Heteronuclear Nuclear Magnetic Resonance Experiments for Studies of Protein Conformation. M. Rance, W.J. Chazin, C. Dalvit, and P.E. Wright, Multiple-Quantum Nuclear Magnetic Resonance. A. Bax, S.W. Sparks, and D.A. Torchia, Detection of Insensitive Nuclei. A. Bax, Homonuclear Hartmann-Hahn Experiments. B.A. Borgias and T.L. James, Two-Dimensional Nuclear Overhauser Effect: Complete Relaxation Matrix Analysis. N. Niccolai and C. Rossi, Selective Relaxation Techniques. L.R. Brown and B.T. Farmer II, Rotating Frame Nuclear Overhauser Effect. J.C. Hoch, Modern Spectrum Analysis in Nuclear Magnetic Resonance: Alternatives to Fourier Transform. S.J. Opella and P.L. Stewart, Solid State Nuclear Magnetic Resonance Structural Studies of Proteins. Enzyme Dynamics: Rate Constants: B.D.N. Rao, Nuclear Magnetic Resonance Line-Shape Analysis and Determination of Exchange Rates. J.J Led, H. Gesmar, and F. Abildgaard, Applicability of Magnetization Transfer Nuclear Magnetic Resonance to Study Chemical Exchange Reactions. B. Berkowitz and R.S. Balaban , Two-Dimensional Nuclear Magnetic Resonance Studies of Enzyme Kinetics and Metabolites in Vivo. P. R*adosch, Isotope Exchange. Molecular Motions: R.E. London, Interpreting Protein Dynamics with Nuclear Magnetic Resonance Relaxation Measurements. M.A. Keniry, Solid-State Deuterium Nuclear Magnetic Resonance Spectroscopy of Proteins. T. Schleich, C.F. Morgan, and G.H. Caines, Protein Rotational Correlation Times by Carbon-13 Rotating-Frame Spin-Lattice Relaxation in Presence of Off-Resonance Radiofrequency Field. R.L. Haner and T. Schleich, Measurement of Translational Motion by Pulse-Gradient Spin-Echo Nuclear Magnetic Resonance. H. Roder, Structural Characterization of Protein-Folding Intermediates by Proton Nuclear Magnetic Resonance and Hydrogen Exchange. Appendix: Computer Programs Related to Nuclear Magnetic Resonance: Availability, Summaries, and Critiques. Author Index. Subject Index.