Novel Psychoactive Substances book cover

Novel Psychoactive Substances

Classification, Pharmacology and Toxicology

Novel Psychoactive Substances: Classification, Pharmacology and Toxicology provides readers with background on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." This book also covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance followed by a discussion of the acute and chronic harm or toxicity associated with the substance. Written by international experts in the field, this multi-authored book is a valuable reference for scientists, clinicians, academics, and regulatory and law enforcement professionals.


Research scientists and academics in pharmacology and toxicology, biochemists and healthcare professionals, including physicians, nurses and paramedics, law enforcement and legislative authorities.

Hardbound, 440 Pages

Published: August 2013

Imprint: Academic Press

ISBN: 978-0-12-415816-0


  • "The background, analytical techniques, and individual novel psychoactive substances are discussed by researchers in pharmaceuticals, law, public health, and various medical specialties. The topics include a global perspective on monitoring them, analytical techniques for detecting them and their metabolites, synthetic amphetamine derivatives, aminoindane analogues, ketamine, synthetic cannabinoid receptor agonists, natural fungal and herbal substances, and benzofurans and benzodifurans."--Reference & Research Book News, December 2013
    "This reference book comprehensively collates a vast range of facts and details about the recently much debated topic of novel psychoactive substances, including the much talked about ‘legal highs’…This book would be a useful reference source for those with a keen interest in novel psychoactive substances internationally, and appeal to those working in this specialist area whether in the field of research or academics, or clinically.", December 4, 2013


  • Section 1: Background
    1. Legal Classification of Novel Psychoactive Substances: An International Comparison
    2. Monitoring novel psychoactive substances - a global perspective
    3. Availability and Supply of Novel Psychoactive Substances
    4. Epidemiology and Use of Novel Psychoactive Substances
    5. Social issues in the use of novel psychoactive substances
    Section 2: Analytical Techniques
    6. Analytical techniques for the detection of novel psychoactive substances and their metabolites
    Section 3: Individual Novel Psychoactive Substances
    7. Synthetic Amphetamines including novel MDMA analogues
    8. 1-benzylpiperazine and other piperazines
    9. 4-methylmethcathinone (mephedrone) and other synthetic cathinones
    10. Pipradrol and pripradrol derivatives
    11. Aminoindanes and related compounds
    12. Gamma-hydrogybutyrate and its analogues
    13. Ketamine
    14. Synthetic cannabinoid receptor agonists
    15. Herbal novel psychoactive substances
    16. Tryptamines
    17. Benzodifurans
    18. Miscellaneous compounds


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