Nitric Oxide

Edited by

  • Bruno Tota, Universita della Calabria, Arcavacata de Rende, Italy
  • Barry Trimmer, Tufts University School of Medicine, Boston, MA, USA

This volume provides a novel insight to the evolutionary and comparative aspects of nitric oxide- nitric oxide synthase system as a central regulator of invertebrate and vertebrate homeostasis. By critically selecting and summarizing the ever–increasing number of original studies, these presentations review a variety of important signalling and modulatory roles played by nitric oxide at molecular, cell, organ and organ system levels. It addresses not only specialists and graduate students in the field, but also all biologists concerned with how this unique, gaseous, pleiotropic molecule has been employed by living systems, uncovering a new dimension of the wonders of life.
View full description


Experimental biologists, researchers in developmental cell and comparative biology within animal and plant biology.


Book information

  • Published: June 2007
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-53119-3

Table of Contents

1. On the Comparative Biology of NO Synthetic Pathways: Parallel Evolution of NO-Mediated SignalingLeonid L. Moroz and Andrea B. Kohn 2. Nitric Oxide Biogenesis, Signalling and Roles in Molluscs: The Sepia officinalis ParadigmAnna Palumbo and Marco d’Ischia3. Soluble Guanylyl Cyclases in Invertebrates: Targets for NO and O2David B. Morton and Anke Vermehren4. Nitric Oxide Signalling in Insect Epithelial TransportShireen-A. Davies5. Nitric Oxide/Cyclic GMP Signaling and Insect BehaviorRalf Heinrich and Geoffrey K. Ganter6. Impact of Nitrative/Nitrosative Stress in Mitochondria: Unraveling Targets for Malaria ChemotherapyShirley Luckhart, Kazunobu Kato and Cecilia Giulivi7. Effects of S-Nitrosation of Nitric Oxide SynthaseDouglas A. Mitchell, Thomas Michel and Michael A. Marletta8. Regulatory Role and Evolution of Unconventional NOS-Related RNAsSergei Korneev and Michael O’Shea9. The Role of Blood Nitrite in the Control of Hypoxic VasodilationAngela Fago and Frank B. Jensen10. Nitrite is a Vascular Store of NO which Mediates Hypoxic Signaling and Protects against Ischemia/Reperfusion InjuryCameron Dezfulian, Mark T. Gladwin and Sruti Shiva11. Nitric Oxide and the Zebrafish (Danio rerio): Developmental Neurobiology and Brain NeurogenesisBo Holmqvist, Lars Ebbesson and Per Alm12. NO in the Development of FishBernd Pelster13. Role of Nitric Oxide in Vascular Regulation in FishClaudio Agnisola and Daniela Pellegrino14. NOS Distribution and NO Control of Cardiac Performance in Fish and Amphibian HeartsBruno Tota, Sandra Imbrogno, Rosa Mazza and Alfonsina Gattuso15. Nitric Oxide and Histamine in Hibernation and NeuroprotectionPertti Panula, Giuseppina Giusi, Rosa Maria Facciolo, Tina Sallmen, Minamaija Lintunen and Marcello Canonaco16. Nitric Oxide, Peroxynitrite and Matrix Metalloproteinases: Insight into the Pathogenesis of SepsisJonathan Cena, Ava K. Chow and Richard Schulz