Handbook of Clinical Neurology Series (Series Editors: Aminoff, Boller, Swaab)

Edited by

  • Alex Tselis, Department of Neurology, Detroit Medical Center, Wayne State University, Detroit, MI, USA
  • John Booss, Virology Labs, West Haven, CT, USA

This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology.

Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere.

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Clinical neurologists at tertiary centers and neuroscience researchers


Book information

  • Published: August 2014
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-53488-0

Table of Contents

Section 1 Introduction
1. A History of Viral Infections of the Central Nervous System: Foundations, Milestones, and Patterns 
2. Basics of virology 
3. Neuroepidemiology and the Epidemiology of Viral Infections of the Nervous System 
4. Clinical Approach to the Syndromes of Encephalitis, Myelitis and Meningitis   
5. Laboratory Diagnosis of Viral Disease  
6. Neuroimaging of Viral Infections of the Central Nervous System  
7. Viral Neuropathogenesis  
8. Neuropathology of viral infections 
9. Innate immune viral recognition: relevance to CNS infections 
10. Adaptive immune response to viral infections in the central nervous system
Section 2 DNA viruses
11. Herpes simplex virus 
12. Varicella zoster 
13. Epstein-Barr virus infections of the nervous system 
14. Cytomegalovirus infections of the adult human nervous system 
15. Congenital Cytomegalovirus Infection 
16. Human herpesvirus-6 and the nervous system 
17. Progressive multifocal leukoencephalopathy 
Section 3  RNA viruses
18. Enterovirus/Picornavirus infections 
19. The equine encephalitides 
20. West Nile and St. Louis encephalitis viruses 
21. The Bunyaviridae 
22. Human endogenous retroviruses and the nervous system 
23. Central Nervous System HIV-1 Infection 
24. Neurological disease due to HTLV-1 infection 
25. Tick-Borne Encephalitis  
26. Japanese Encephalitis Virus Infection 
27. Measles virus and the nervous system  
28. Mumps and rubella 
29. Rabies 
30. Neurologic aspects of influenza viruses 
31. Neurological complications of hepatic viruses 
32. Henipavirus Encephalitis 
33. Diseases of the Central Nervous System Caused by Lymphocytic Choriomeningitis Virus and other Arenaviruses 
Section 4  Other Topics Concerning Viral or Presumed Viral Infections of the CNS
34. Nervous system viral infections in immunocompromised hosts 
35. Acute Disseminated Encephalomyelitis 
36. Vaccines and viral / toxin associated neurological infections 
37. Encephalitis Lethargica (von Economo's encephalitis) 
38. Bell’s Palsy and Vestibular Neuronitis