Progress in Restorative Neuroscience and Neurology

Edited by

  • Joost Verhaagen, Laboratory for Neuroregeneration, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands
  • Elly Hol
  • Inge Huitinga
  • Jan Wijnholds
  • Arthur Bergen
  • Gerard Boer
  • Dick Swaab, Netherlands Institute for Brain Research, University of Amsterdam, Amsterdam, The Netherlands

This book focuses on the exciting recent progress in restorative neurology and neuroscience. The book includes chapters on major neurodegenerative disorders of the brain and the visual system, including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, macular degeneration, retinitis pigmentosa, glaucoma, spinal cord trauma, and multiple sclerosis. The primary goal of the book is to give an overview of new developments in translational research and in potential therapeutic strategies, including stem cell therapy, immunotherapy, gene therapy, pharmacotherapy, neuroprostheses and deep brain stimulation.
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neuroscientistspsychologistspsychiatristsbasic and clinical researches in medical fields


Book information

  • Published: September 2009
  • Imprint: ELSEVIER
  • ISBN: 978-0-12-374511-8

Table of Contents

Section - Stem Cells Jeffrey Macklis - Boston, USA Stem cell recruitement in the adult cortex following spinal cord injury Scott Whittemore - Louisville, USA Application of embryonic stem cells in spinal cord repair Peter Burbach - Utrecht, The Netherlands Molecular programming of stem cells into mesodiencephalic dopaminergic neurons Ole Isacson - Belmont, USA Stem cell transplantation in Parkinson disease Robin Ali - London, UK Retinal repair by transplantation of photoreceptors Thomas Reh - Seattle, USA Efficient generation of retinal progenitor cells from human embryonic stem cells Maurice Curtis - Gotenborg, Sweden Discovery of a rostral migratory stream in the adult human brain Magdalena Götz - Munich, Germany Glial cells as stem cells ? a new view on reactive gliosis Urban Lendahl - Stockholm, Sweden Molecular regulation of stem cell differentiation Anders Björklund - Lund, Sweden Cell and gene therapy repair stategies for Parkinson disease Section Immunotherapy and vaccination therapy Roger Nitsch - Zurich, Switzerland Immunotherapy of Alzheimer's disease Cynthia Lemere, Boston, USA Developing novel immunogens for effective and safe Alzheimer disease vaccine Frank Baas - Amsterdam, the Netherlands Complement therapy promotes peripheral nerve regeneration Philip Popovich - Columbus, USA T-cell and macrophage involvement in neuroregeneration Hans van Noort - Rijswijk, The Netherlands Toll-like receptors in the CNS: implications for neurodegeneration and repair Section Gene Therapy Alan Harvey - Perth, Australia Gene therapy and transplantation in CNS repair: the visual system Raymond Bartus - San Diego, USA Gene therapy for Alzheimer's and Parkinson's disease Krys Bankiewicz - San Francisco, USA AAV-AADC gene therapy for Parkinson disease Martijn Tannemaat - Amsterdam, the Netherlands Promoting regeneration of injured peripheral nerves and avulsed spinal ventral roots by gene therapy Mimoun Azzouz - Sheffield, UK Gene therapy for ALS based on retrograde delivery of transgenes with equine LV vectors Bill Hauswirth - Gainesville, USA Cone photoreceptor targeted gene therapyPharmacotherapy Iqbal Sayeed - Atlanta, USA Progesterone as a neuroprotective factor in traumatic and ischemic brain injury Stefan Gold - Los Angeles, USA Oestrogen and testosterone replacement therapies in neurologic and psychiatric disorders Reinier Schlingemann - Amsterdam, the Netherlands Treatment of retinal diseases with VEGF antagonists Hans-Werner Müller - Düsseldorf, Germany Pharmacological modification of the extracellular matrix to promote regeneration of the injured brain and spinal cord Yvo Roos - Amsterdamdam, the Netherlands First aid for the brain: successful reanimation strategies after stroke Fabrizio Benedetti - Turin, Italy Placebo responses in neurological disordersNeuroprostheses Thomas Stieglitz - Freiburg, Germany Brain-computer interfaces Gerald Chader - Los Angeles, USA Visual performance with retinal prostheses Vittorio Colletti - Verona, Italy Alternative neurosurgical approaches for auditory brain implants Richard Normann - Salt Lake City, USA Neuronal ensemble control of prosthetic devices by a human with tetraplegia Edward Tehovnik ? Cambridge, MA, USA Microstimulation of the visual cortex to restore vision Miguel Nicolelis - Durham, USA Control of artificial limb in monkeys: feedback by neural stimulationDeep Brain Stimulation, FES and TMS Alim-Louis Benabid - Grenoble, France Deep brain stimulation for neurological disorders: an historical perspective Reggie Edgerton - Los Angeles, USA Potential for restoring neuromotor function via activity-dependent mechanisms Vivian Mushahwar - Edmonton, Canada Intraspinal microstimulation and oscillating field stimulation Damiaan Denys - Amsterdam, the Netherlands Deep brain stimulation: obsessive compulsive disorder Diego Centonze - Rome, Italy Repetitive transcranial magnetic stimulation of the motor cortex ameliorates spasticity in multiple sclerosisMechanisms of spontaneous plasticity and regeneration Christian Lohmann ? Amsterdam, The Netherlands Simultaneous imaging of morphological plasticity and calcium dynamics in dendrites Catherine Lubetzki - Paris, France Axonal signals in central nervous system demyelination: the semaphorins Massimo Filippi - Milan, Italy Magnetic resonance techniques to quantify tissue damage, tissue repair and functional cortical reorganization in multiple sclerosis Henning Voss - New York, USA Diffusion tensor imaging as a tool to study neuronal plasticity and regeneration James Fawcett - Cambridge, UK Molecular control of brain plasticity and repair