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Neuropathology

A Volume in the High Yield Pathology Series (Expert Consult - Online and Print)

By
  • Anthony Yachnis, MD, Department of Pathology, Immunology, and Laboratory Medicine, Universiity of Florida College of Medicine, Gainesville, Florida
  • Marie Rivera-Zengotita, MD, Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida

Save time diagnosing neuropathology specimens with Neuropathology , part of the growing High-Yield Pathology Series . Dr. Anthony Yachnis and Dr. Marie Rivera-Zengotita help you review the key features of neuropathology specimens, recognize the classic look of each disease, and quickly confirm your diagnosis. A logical format, excellent color photographs, concise bulleted text, and authoritative content will help you accurately identify hundreds of discrete disease entities.

Hardbound, 368 Pages

Published: February 2013

Imprint: Saunders

ISBN: 978-1-4160-6220-2

Contents

    1. BASIC REACTIONS
    1. Cerebral Edema
    2. Hydrocephalus
    3. Herniations
    1. DEVELOPMENTAL DISORDERS
    1. Malformations

      2. Neural Tube Defects

      Holoprosencephaly

      Posterior Fossa: Chiari Malformations

      Cerebellar Vermis Malformations

      Lhermitte-Duclos Disease

      Neuronal Migration Defects

    2. Acquired Developmental Defects

    Germinal Matrix Hemorrhage

    Periventricular Leukomalacia

    Gray Matter Lesions

    Porencephaly

    1. CEREBROVASCULAR DISORDERS
    1. Cerebral Ischemia and Hypertensive Changes

      2. Ischemic Cerebrovascular Disease

      Hypertensive Cerebrovascular Disease: Ischemic Changes

      Hypertensive Cerebrovascular Disease: Spontaneous Intracerebral Hemorrhage

      Hypertensive Cerebrovascular Disease: Posterior Reversible Encephalopathy Syndrome (PRES)

    2. Intracranial Aneurysms

      3. Saccular ("Berry") Aneurysms

      Fusiform Aneurysms

      Infective ("Mycotic") Aneurysms

    3. Vascular Malformations

      4. Arteriovenous Malformations (AVM)

      Cavernous Angiomas (CA)

      Capillary Telangiectasis

      Venous Angioma

    4. Vasculitis

      5. Giant Cell Arteritis

      Polyarteritis Nodosa (PAN)

      Primary CNS Angiitis

    5. Inherited Cerebrovascular Diseases

    Cerebral Amyloid Angiopathy

    Cerebral Autosomal Dominant Ateriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)

    Moyamoya Syndrome

    1. TRAUMA

    1. Closed vs Open (Penetrating) Head Trauma

      2. Contusion/Laceration (Including Coup and Contra Coup Lesions)

      Diffuse Axonal Injury (Diffuse Traumatic Brain Injury)

    2. Traumatic Intracranial Hemorrhage

    Epidural Hematoma

    Subdural Hematoma

    1. BRAIN TUMORS
    1. Diffuse Gliomas-Astrocytic

      2. Diffuse Astrocytoma

      Anaplastic Astrocytoma

      Glioblastoma

      Glioblastoma Variants

    2. Diffuse Gliomas-Oligdendroglial

      3. Oligodendroglioma

      Anaplastic Oligodendroglioma

      Mixed Glioma (Oligosatrocytoma, Anaplastic Oligoastrocytoma)

      Gliomatosis Cerebri

    3. Other Astrocytic Tumors

      4. Pleomorphic Xanthoastrocytoma (PXA)

      Pilocytic Astrocytoma

      Subependymal Giant Cell Astrocytoma

    4. Ependymomas and Subependymoma

      5. Ependymoma

      Anaplastic Ependymoma

      Myxopapillary Ependymoma

      Subependymoma

    5. Tumors with Ependymal-like Features

      6. Angiocentric Glioma

      Chordoid Glioma

      Astroblastoma

    6. Choroid Plexus Tumors

      7. Choroid Plexus Papilloma

      Choroid Plexus Carcinoma

    7. Neuronal and Glioneuronal Tumors

      8. Ganglion Cell Tumors

      Desmoplastic Infantile Astrocytoma/Ganglioglioma

      Central Neurocytoma

      Dysembryoplastic Neuroepithelial Tumor (DNET)

      Papillary Glioneuronal Tumor

      Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle

    8. Embryonal (Primitive) Neuroepithelial Tumors

      9. Medulloblastoma

      Central Nervous System - Primitive Neuroectodermal Tumor (CNS-PNET)

      Atypical Teratoid/Rhabdoid Tumors (AT/RT)

    9. Meningiomas (Tumors of the Meninges)

      10. Meningioma: Overview and General Characteristics

      Meningioma: WHO Grade I Variants

      Atypical Meningioma

      Malignant (Anaplastic) Meningiomas

      Hemangiopericytoma: Solitary Fibrous Tumor

    10. Nerve Sheath Tumors

      11. Schwannoma

      Neurofibroma

      Perineurioma

      Malignant Peripheral Nerve Sheath Tumor (MPNST)

    11. Primary CNS Lymphoma (PCNSL)

    12. Pineal Parenchymal Tumors

      13. Pineocytoma

      Pineal Parenchymal Tumor of Intermediate Differentiation

      Pineoblastoma

      Papillary Tumor of the Pineal Region

    13. Germ Cell Tumors of the Central Nervous System

      14. Germinoma

      Other Germ Cell Tumors

    14. Hemangioblastoma
    15. Sellar and Suprasellar Tumors

      16. Pituitary adenomas

      Pituicytoma

      Cranopharyngioma

      Rathke cleft cyst

      Langerhans cell histiocytosis

    16. Primary Melanocytic Tumors of the Central Nervous System
    17. Central Nervous System Cysts
    18. Metastatic Brain Tumors
    19. Tumors of the Skull Base

              Chordoma of Skull Base

              Chondrosarcoma of Skull Base

    1. INFECTIOUS DISEASES

    1. Bacterial Infections

      2. Acute Purulent Meningitis

      Cerebral Bacterial Abscess

      Nocardia/Actinomycetes Species

      Mycobacterial Infection

      Neurosyphilis

    2. Mycoses

      3. Cerebral Cryptococcosis

      Aspergillosis

      Mucormycosis

      Candidiasis

    3. Parasitic Infections

      4. Cerebral Toxoplasmosis

      Cerebral Cystecercosis

      Primary Amoebic Meningoencephalitis

      Granulomatous Amoebic Encephalitis

      Cerebral Malaria

    4. Viral Infections

      5. General viral effects on the nervous system

      Herpes Simplex Encephalitis

      Cytomegalovirus Encephalitis

      Rabies encephalitis

      Arboviruses

      Progressive Multifocal Leukoencephalopathy

    5. Neuropathology of AIDS

      6. Primary effects of HIV infection

      HIV-Associated Vacuolar Myelopathy (HAM)

      Opportunistic CNS Infections in AIDS

      CNS Immune Reconstitution Inflammatory Syndrome (Neuro-IRIS)

    6. Prion Diseases

               Prion-related diseases (Overview)

              Creutzfeldt-Jacob disease

              Other prion-related diseases

    1. Neurodegenerative disorders
    1. Alzheimer’s Disease
    2. Frontotemporal Lobar Degenerations and Related Tauopathies

      3. Corticobasal Degeneration (Rebeiz Disease)

      Progressive Supranuclear Palsy (PSP: Steele-Richardson-Olszewski Syndrome)

      Pick Disease

      Frontotemporal Lobar Degeneration: Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17)

    3. Frontotemporal Lobar Degenerations with Ubiquitin-Inclusions (FTLD-U/FTLD-MND (TDP-43)
    4. Parkinson’s Disease and Related Alpha-Synucleinopathies

      5. Parkinson’s Disease

      Dementia with Lewy Bodies

      Multiple System Atrophy (MSA)

    5. Amyotrophic Lateral Sclerosis (ALS)
    6. Triple-Repeat Inherited Neurodegenerations

      7. Huntington Disease

      Autosomal Recessive Spinocerebellar Degeneration (Friedrich’s Ataxia)

      Autosomal Dominant Spinocerebellar Ataxias (SCA)

      Fragile X Tremor / Ataxia Syndrome

    7. Neuroaxonal Dystrophies

      8. Neurodegeneration with brain iron accumulation type 1 (NBIA 1)

      Other inherited neuroaxonal dystrophies

    8. Vascular Dementia and Binswanger Disease
    1. DEMYELINATING DISEASES
    1. Multiple sclerosis

      2. Multiple Sclerosis

      Neuromyelitis Optica Spectrum Disorders

    2. Acute Disseminated Leukoencephalitis
    3. Acute Hemorrhagic Leukoencephalitis (Hurst Disease)
    4. Tumefactive Demyelinating Lesions (TDL)
    1. TOXIC, NUTRITIONAL, METABOLIC DISEASE s

      2. A. Toxic Injury

      Toxic Leukoencephalopathy

      Carbon monoxide

      Ethanol-related injury (including superior vermis atrophy and central pontine myelinolysis)

      Hepatic encephalopathy

      B. Nutritional Diseases

      Wernicke-Korsakoff disease

      Subacute Combined Degeneration

      C. Metabolic Diseases

      Neuronal Storage Disease

      Leukodystrophies

      Neuronal Ceroid Lipofuscinosis

      Wilson Disease (Hepatolenticular Degeneration)

      Alexander disease

    2. Neuromuscular disorders

    1. Peripheral Nerve Disease

      2. Basic reactions in peripheral nerve disorders

      Immune-Mediated Inflammatory Neuropathies

      Charcot-Marie-Tooth disease and related congenital neuropathies

    2. Skeletal Muscle Diseases

    Essential Features: Myopathic versus Neurogenic Changes

    Dermatomyositis

    Polymyositis

    Inclusion Body Myopathy and Myositis

    Dystrophinopathies (Duchenne and Becker Muscular Dystrophy

    Myotonic Dystrophies

    Periodic Paralysis

    Limb-Girdle Muscular Dystrophies

    Nemaline Myopathy

    Central Core Disease

    Pompe Disease

    McArdle Disease

    Mitochondiral Myopathies

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