Neuropathology book cover

Neuropathology

A Volume in the High Yield Pathology Series (Expert Consult - Online and Print)

Save time diagnosing neuropathology specimens with Neuropathology, part of the growing High-Yield Pathology Series. Dr. Anthony Yachnis and Dr. Marie Rivera-Zengotita help you review the key features of neuropathology specimens, recognize the classic look of each disease, and quickly confirm your diagnosis. A logical format, excellent color photographs, concise bulleted text, and authoritative content will help you accurately identify hundreds of discrete disease entities.

Hardbound, 368 Pages

Published: February 2013

Imprint: Saunders

ISBN: 978-1-4160-6220-2

Contents

  • I. BASIC REACTIONS

    A. Cerebral Edema

    B. Hydrocephalus

    C. Herniations

    II. DEVELOPMENTAL DISORDERS

    A. Malformations

    Neural Tube Defects

    Holoprosencephaly

    Posterior Fossa: Chiari Malformations

    Cerebellar Vermis Malformations

    Lhermitte-Duclos Disease

    Neuronal Migration Defects

    B. Acquired Developmental Defects

    Germinal Matrix Hemorrhage

    Periventricular Leukomalacia

    Gray Matter Lesions

    Porencephaly

    III. CEREBROVASCULAR DISORDERS

    A. Cerebral Ischemia and Hypertensive Changes

    Ischemic Cerebrovascular Disease

    Hypertensive Cerebrovascular Disease: Ischemic Changes

    Hypertensive Cerebrovascular Disease: Spontaneous Intracerebral Hemorrhage

    Hypertensive Cerebrovascular Disease: Posterior Reversible Encephalopathy Syndrome (PRES)

    B. Intracranial Aneurysms

    Saccular ("Berry") Aneurysms

    Fusiform Aneurysms

    Infective ("Mycotic") Aneurysms

    C. Vascular Malformations

    Arteriovenous Malformations (AVM)

    Cavernous Angiomas (CA)

    Capillary Telangiectasis

    Venous Angioma

    D. Vasculitis

    Giant Cell Arteritis

    Polyarteritis Nodosa (PAN)

    Primary CNS Angiitis

    E. Inherited Cerebrovascular Diseases

    Cerebral Amyloid Angiopathy

    Cerebral Autosomal Dominant Ateriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL)

    Moyamoya Syndrome

    IV. TRAUMA

    A. Closed vs Open (Penetrating) Head Trauma

    Contusion/Laceration (Including Coup and Contra Coup Lesions)

    Diffuse Axonal Injury (Diffuse Traumatic Brain Injury)

    B. Traumatic Intracranial Hemorrhage

    Epidural Hematoma

    Subdural Hematoma

    V. BRAIN TUMORS

    A. Diffuse Gliomas-Astrocytic

    Diffuse Astrocytoma

    Anaplastic Astrocytoma

    Glioblastoma

    Glioblastoma Variants

    B. Diffuse Gliomas-Oligdendroglial

    Oligodendroglioma

    Anaplastic Oligodendroglioma

    Mixed Glioma (Oligosatrocytoma, Anaplastic Oligoastrocytoma)

    Gliomatosis Cerebri

    C. Other Astrocytic Tumors

    Pleomorphic Xanthoastrocytoma (PXA)

    Pilocytic Astrocytoma

    Subependymal Giant Cell Astrocytoma

    D. Ependymomas and Subependymoma

    Ependymoma

    Anaplastic Ependymoma

    Myxopapillary Ependymoma

    Subependymoma

    E. Tumors with Ependymal-like Features

    Angiocentric Glioma

    Chordoid Glioma

    Astroblastoma

    F. Choroid Plexus Tumors

    Choroid Plexus Papilloma

    Choroid Plexus Carcinoma

    G. Neuronal and Glioneuronal Tumors

    Ganglion Cell Tumors

    Desmoplastic Infantile Astrocytoma/Ganglioglioma

    Central Neurocytoma

    Dysembryoplastic Neuroepithelial Tumor (DNET)

    Papillary Glioneuronal Tumor

    Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle

    H. Embryonal (Primitive) Neuroepithelial Tumors

    Medulloblastoma

    Central Nervous System - Primitive Neuroectodermal Tumor (CNS-PNET)

    Atypical Teratoid/Rhabdoid Tumors (AT/RT)

    I. Meningiomas (Tumors of the Meninges)

    Meningioma: Overview and General Characteristics

    Meningioma: WHO Grade I Variants

    Atypical Meningioma

    Malignant (Anaplastic) Meningiomas

    Hemangiopericytoma: Solitary Fibrous Tumor

    J. Nerve Sheath Tumors

    Schwannoma

    Neurofibroma

    Perineurioma

    Malignant Peripheral Nerve Sheath Tumor (MPNST)

    K. Primary CNS Lymphoma (PCNSL)

    L. Pineal Parenchymal Tumors

    Pineocytoma

    Pineal Parenchymal Tumor of Intermediate Differentiation

    Pineoblastoma

    Papillary Tumor of the Pineal Region

    M. Germ Cell Tumors of the Central Nervous System

    Germinoma

    Other Germ Cell Tumors

    N. Hemangioblastoma

    O. Sellar and Suprasellar Tumors

    Pituitary adenomas

    Pituicytoma

    Cranopharyngioma

    Rathke cleft cyst

    Langerhans cell histiocytosis

    P. Primary Melanocytic Tumors of the Central Nervous System

    Q. Central Nervous System Cysts

    R. Metastatic Brain Tumors

    S. Tumors of the Skull Base

    Chordoma of Skull Base

    Chondrosarcoma of Skull Base

    VI. INFECTIOUS DISEASES

    A. Bacterial Infections

    Acute Purulent Meningitis

    Cerebral Bacterial Abscess

    Nocardia/Actinomycetes Species

    Mycobacterial Infection

    Neurosyphilis

    B. Mycoses

    Cerebral Cryptococcosis

    Aspergillosis

    Mucormycosis

    Candidiasis

    C. Parasitic Infections

    Cerebral Toxoplasmosis

    Cerebral Cystecercosis

    Primary Amoebic Meningoencephalitis

    Granulomatous Amoebic Encephalitis

    Cerebral Malaria

    D. Viral Infections

    General viral effects on the nervous system

    Herpes Simplex Encephalitis

    Cytomegalovirus Encephalitis

    Rabies encephalitis

    Arboviruses

    Progressive Multifocal Leukoencephalopathy

    E. Neuropathology of AIDS

    Primary effects of HIV infection

    HIV-Associated Vacuolar Myelopathy (HAM)

    Opportunistic CNS Infections in AIDS

    CNS Immune Reconstitution Inflammatory Syndrome (Neuro-IRIS)

    F. Prion Diseases

    Prion-related diseases (Overview)

    Creutzfeldt-Jacob disease

    Other prion-related diseases

    VII. Neurodegenerative disorders

    A. Alzheimer’s Disease

    B. Frontotemporal Lobar Degenerations and Related Tauopathies

    Corticobasal Degeneration (Rebeiz Disease)

    Progressive Supranuclear Palsy (PSP: Steele-Richardson-Olszewski Syndrome)

    Pick Disease

    Frontotemporal Lobar Degeneration: Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17)

    C. Frontotemporal Lobar Degenerations with Ubiquitin-Inclusions (FTLD-U/FTLD-MND (TDP-43)

    D. Parkinson’s Disease and Related Alpha-Synucleinopathies

    Parkinson’s Disease

    Dementia with Lewy Bodies

    Multiple System Atrophy (MSA)

    E. Amyotrophic Lateral Sclerosis (ALS)

    F. Triple-Repeat Inherited Neurodegenerations

    Huntington Disease

    Autosomal Recessive Spinocerebellar Degeneration (Friedrich’s Ataxia)

    Autosomal Dominant Spinocerebellar Ataxias (SCA)

    Fragile X Tremor / Ataxia Syndrome

    G. Neuroaxonal Dystrophies

    Neurodegeneration with brain iron accumulation type 1 (NBIA 1)

    Other inherited neuroaxonal dystrophies

    H. Vascular Dementia and Binswanger Disease

    VIII. DEMYELINATING DISEASES

    A. Multiple sclerosis

    Multiple Sclerosis

    Neuromyelitis Optica Spectrum Disorders

    B. Acute Disseminated Leukoencephalitis

    C. Acute Hemorrhagic Leukoencephalitis (Hurst Disease)

    D. Tumefactive Demyelinating Lesions (TDL)

    IX. TOXIC, NUTRITIONAL, METABOLIC DISEASES

    A. Toxic Injury

    Toxic Leukoencephalopathy

    Carbon monoxide

    Ethanol-related injury (including superior vermis atrophy and central pontine myelinolysis)

    Hepatic encephalopathy

    B. Nutritional Diseases

    Wernicke-Korsakoff disease

    Subacute Combined Degeneration

    C. Metabolic Diseases

    Neuronal Storage Disease

    Leukodystrophies

    Neuronal Ceroid Lipofuscinosis

    Wilson Disease (Hepatolenticular Degeneration)

    Alexander disease

    X. Neuromuscular disorders

    A. Peripheral Nerve Disease

    Basic reactions in peripheral nerve disorders

    Immune-Mediated Inflammatory Neuropathies

    Charcot-Marie-Tooth disease and related congenital neuropathies

    B. Skeletal Muscle Diseases

    Essential Features: Myopathic versus Neurogenic Changes

    Dermatomyositis

    Polymyositis

    Inclusion Body Myopathy and Myositis

    Dystrophinopathies (Duchenne and Becker Muscular Dystrophy

    Myotonic Dystrophies

    Periodic Paralysis

    Limb-Girdle Muscular Dystrophies

    Nemaline Myopathy

    Central Core Disease

    Pompe Disease

    McArdle Disease

    Mitochondiral Myopathies

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