Neuro-Oncology, Part II

Handbook of Clinical Neurology (Series editors: Aminoff, Boller, Swaab)


  • Wolfgang Grisold, Head of Department, Neurologic Department and LBI for Neuro-Oncology, Kaiser Franz Josef Hospital, Vienna, Austria
  • Riccardo Soffietti, Head, Division of Neuro-Oncology

Handbook of Clinical Neurology: Neuro-Oncology, Part II provides an overview of the most recent developments in the field of neuro-oncology, including new diagnostic imaging techniques, along with immunology, molecular biology, and clinical aspects of different types of tumors. It also considers management and new therapeutic strategies for tumors, such as gene therapy, radiation therapy, and molecularly targeted treatments. Divided into five sections encompassing 33 chapters, the book begins with a description of specific tumor types such as low-grade gliomas, anaplastic astrocytomas, and medulloblastoma and primitive neuroectodermal tumors, along with rare brain tumors like neurofibromatosis and other genetic syndromes. It then discusses tumors at special sites, from brainstem tumors to peripheral nerve tumors, tumors of the meninges, and optic, hypothalamic, and thalamic tumors. It also explains the neurological complications of systemic cancer and the adverse effects of some treatments. Clinicians and neuroscientists, as well as researchers who read this book, will gain a better understanding of the clinical features and management of the neurological manifestations of tumors.
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Book information

  • Published: February 2012
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-53502-3


"…an unparalleled reputation as the world's most comprehensive source of information in neurology...Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.", April 24, 2013

Table of Contents




Section 4 Specific tumor types

    29. Low-grade gliomas

    30. Anaplastic astrocytomas

    31. Anaplastic oligodendroglial tumors

    32. Glioblastoma

    33. Gliomatosis cerebri

    34. Primary central nervous system lymphoma

    35. Medulloblastoma and primitive neuroectodermal tumors

Section 5 Rare brain tumors

    36. Ependymomas, neuronal and mixed neuronal-glial tumors, dysembroblastic neuroepithelial tumors, pleomorphic xanthoastrocytomas, and pilocytic astrocytomas

    37. Neurofibromatosis and other genetic syndromes

Section 6 Tumors at special sites

    38. Brainstem tumors

    39. Optic, hypothalamic, and thalamic tumors

    40. Pineal parenchymal tumors, embryonal tumors, and germ cell tumors

    41. Tumors of the cerebellopontine angle

    42. Tumors of the meninges

    43. The management of skull base tumors

    44. Peripheral nerve tumors

Section 7 Neurological complications of systemic cancer

    45. General oncology and neurological complications

    46. Neurological complications of solid tumors

    47. Neurological complications of leukemia and lymphoma

    48. Neurological complications in plasma cell dyscrasias

    49. Brain metastases

    50. Neoplastic meningitis

    51. Spinal cord involvement

    52. Neuromuscular complications

    53. Neurovascular complications of solid tumors and hematological neoplasms

    54. Infectious, metabolic, and endocrine complications

    55. Central nervous system paraneoplastic disease

    56. Paraneoplastic disorders of the peripheral nervous system

Section 8 Complications from treatments

    57. Complications of chemotherapy in neuro-oncology

    58. Complications of radiotherapy to the central nervous system

    59. Neurological complications of chemotherapy to the central nervous system

    60. Neurological complications of chemotherapy to the peripheral nervous system

    61. General and neurological complications of targeted therapy