Neuro-Oncology Part I
Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)
Edited by- Wolfgang Grisold, Head of Department, Neurologic Department and LBI for Neuro-Oncology, Kaiser Franz Josef Hospital, Vienna, Austria
- Riccardo Soffietti, Department of Neuroscience, Neuro-Oncology, University of Torino, Italy.
This volume highlights recent developments in neuro-oncology that are not only increasing the survival rate of patients, but also improving their quality of life. Through an in-depth exploration of new therapies, including advanced diagnostic tools and a fresh perspective on molecular biology, immunology, and the clinical aspects of tumors, clinicians will gain a critical understanding of emerging therapies and techniques. Extensive coverage of tumor management and new therapeutic strategies, including gene therapy and molecularly targeted treatments are also explored, providing clinicians with new tools and tactics they can use to treat tumors of the nervous system.
Clinicians will find this handbook to be an invaluable resource for summarizing the present state of scientific and clinical knowledge in the field of neuro-oncology. In addition, practitioners in the field will uncover new tactics and therapies that will aid them in providing optimal neuro-oncological care for their patients.
Handbook of Clinical Neurology
Hardbound, 488 Pages
Published: February 2012
Imprint: Elsevier
ISBN: 978-0-444-52138-5
Contents
SECTION 1 Basic principles
1. Epidemiology of central nervous system tumours
2. Molecular biology of brain tumors
3. Angiogenesis and invasion in cancer
4. Immunology of brain tumors
5. Blood brain barrier and brain edema
6. Stem cells in gliomas
SECTION 2 Diagnostic tools
7. Diagnostic neuropathology of tumors of the central nervous system
8. Neuroimaging
9. Functional imaging in brain surgery
10. Imaging brain tumors with PET, SPECT, ultrasound
11. CSF and laboratory analysis (tumor markers)
12. Electrophysiology and intraoperative neurophysiological monitoring
13. Evaluation and monitoring of peripheral nerve function
14. Evaluation of cognitive functions and quality of life
SECTION 3 Principles of Therapy15. Principles of brain tumor surgery16. Radiotherapy17. Chemotherapy with cytotoxic and cytostatic agents in brain cancer18. Molecularly targeted therapy in Neuro-oncology19. Inhibiting angiogenesis in malignant gliomas20. Immunotherapy of brain tumors21. Gene therapy22. Chemotherapy for brain tumors with polymer drug delivery23. Convection-enhanced delivery of therapeutic agents into the brain24. Management of cognitive deficits and mood disturbance)
25. Steroids and brain tumors
)26. Seizure control in brain tumours27. Cancer pain management and palliative care28. Clinical trials in Neuro-oncology
