Neuro-Oncology Part I book cover

Neuro-Oncology Part I

Handbook of Clinical Neurology (Series Editors: Aminoff, Boller and Swaab)

This volume highlights recent developments in neuro-oncology that are not only increasing the survival rate of patients, but also improving their quality of life. Through an in-depth exploration of new therapies, including advanced diagnostic tools and a fresh perspective on molecular biology, immunology, and the clinical aspects of tumors, clinicians will gain a critical understanding of emerging therapies and techniques. Extensive coverage of tumor management and new therapeutic strategies, including gene therapy and molecularly targeted treatments are also explored, providing clinicians with new tools and tactics they can use to treat tumors of the nervous system.

Clinicians will find this handbook to be an invaluable resource for summarizing the present state of scientific and clinical knowledge in the field of neuro-oncology. In addition, practitioners in the field will uncover new tactics and therapies that will aid them in providing optimal neuro-oncological care for their patients.

Hardbound, 488 Pages

Published: February 2012

Imprint: Elsevier

ISBN: 978-0-444-52138-5



    SECTION 1 Basic principles

    1. Epidemiology of central nervous system tumours

    2. Molecular biology of brain tumors

    3. Angiogenesis and invasion in cancer

    4. Immunology of brain tumors

    5. Blood brain barrier and brain edema

    6. Stem cells in gliomas

    SECTION 2 Diagnostic tools

    7. Diagnostic neuropathology of tumors of the central nervous system

    8. Neuroimaging

    9. Functional imaging in brain surgery

    10. Imaging brain tumors with PET, SPECT, ultrasound

    11. CSF and laboratory analysis (tumor markers)

    12. Electrophysiology and intraoperative neurophysiological monitoring

    13. Evaluation and monitoring of peripheral nerve function

    14. Evaluation of cognitive functions and quality of life

    SECTION 3 Principles of Therapy

    15. Principles of brain tumor surgery

    16. Radiotherapy

    17. Chemotherapy with cytotoxic and cytostatic agents in brain cancer

    18. Molecularly targeted therapy in Neuro-oncology

    19. Inhibiting angiogenesis in malignant gliomas

    20. Immunotherapy of brain tumors

    21. Gene therapy

    22. Chemotherapy for brain tumors with polymer drug delivery

    23. Convection-enhanced delivery of therapeutic agents into the brain

    24. Management of cognitive deficits and mood disturbance


    25. Steroids and brain tumors


    26. Seizure control in brain tumours

    27. Cancer pain management and palliative care

    28. Clinical trials in Neuro-oncology


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