Natural Product Biosynthesis by Microorganisms and Plants Part B book cover

Natural Product Biosynthesis by Microorganisms and Plants Part B

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants.

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Included in series
Methods in Enzymology

Hardbound, 462 Pages

Published: October 2012

Imprint: Academic Press

ISBN: 978-0-12-394291-3


    1. In vivo production of thiopeptide variants
      Feifei Zhang and Wendy L. Kelly
    2. Microviridin biosynthesis
      Thomas K. Hemscheidt
    3. Cyclotide isolation and characterization
      David J. Craik, Sonia Troeira Henriques, Joshua S. Mylne and Conan K. Wang
    4. Ribosomally-encoded cyclic peptide toxins from mushrooms
      Jonathan Walton, Hong Luo, and Heather Hallen-Adams
    5. The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase
      Kento Koketsu, Atsushi Minami, Kenji Watanabe, Hiroki Oguri and Hideaki Oikawa
    6. Discovery and biosynthesis of phosphonate and phosphinate natural products
      Spencer C. Peck, Jiangtao Gao, and Wilfred A. van der Donk
    7. RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins
      Nicholas D. Lanz, Tyler, L. Grove, Camelia Gogonea, Carsten Krebs, and Squire J. Booker
    8. Fe(II)-dependent, uridine-5’-monophosphate α-ketoglutarate dioxygenases in the synthesis of 5’-modified nucleosides
      Zhaoyong Yang, Jason Unrine, Koichi Nonaka, and Steven G. Van Lanen
    9. Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE
      S. M. Barry and Greg Challis
    10. Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example
      Paulina K. Sydor and Greg Challis
    11. The rare fluorinated natural products and biotechnological prospects for fluorine enzymology
      K. K. Jason Chan and David O’Hagan
    12. Enzymatic chlorination and bromination
      Karl-Heinz van Pée
    13. Prenyltransferases of the dimethylallyltryptophan synthase superfamily
      Xia Yu and Shu-Ming Li
    14. Serine carboxypeptidase-like acyltransferases from plants
      Sam T. Mugford and Carsten Milkowski
    15. 4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis
      Jeremy R. Lohman and Ben Shen
    16. Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis
      Shuangjun Lin, Tingting Huang, and Ben Shen
    17. High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer
      Richard W. Gantt and Jon S. Thorson


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