Mucosal Vaccines book cover

Mucosal Vaccines

This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology.

Hardbound, 479 Pages

Published: October 1996

Imprint: Academic Press

ISBN: 978-0-12-410580-5


  • "This book contains several chapters providing a good overall view of the cellular structure and function of the mucosal immune system. The remaining chapters provide a good, broad foundation for understanding the current problems in vaccine research as well as a detailed description of cutting edge research on vaccines against specific mucosal pathogens and vaccines designed to protect specific mucosal sites. The editors have therefore succeeded in summarizing current views and concepts relating to new generations of vaccines and vaccine technologies."

    "In the preface to this book, the editors state that "Mucosal Vaccines summarizes the most current and updated views and concepts related to the development of new generations of vaccines.' This tall order is beautifully delivered in 33 chapters and almost 500 pages by contributing authors, all respected experts in their fields... The editors have done an excellent job of putting together the many chapters in logical and understandable groupings, and the authors should be cited for their excellent contributions."
    --ASM NEWS


  • Introduction:P.L. Ogra, Mucosal Immunoprophylaxis.Principles of Mucosal Vaccination:J.R. McGhee, Mucosal Vaccines: From Molecular and Cellular Concepts of Mucosal Immunity to Practical Application.M.R. Neutra and J.-P. Kraehenbuhl, Antigen Uptake by M Cells for Effective Mucosal Vaccines.Mucosal Modulation for Induction of Effective Immunity:C.O. Elson, Cholera Toxin as a Mucosal Adjuvant.J.D. Clements, Unique Characteristics of Escherichia coli Heart-Labile Enterotoxin for Mucosal Immunization.H. Kiyono and C. Czerkinsky, Mucosal Vaccines and Oral Tolerance.Current and New Approaches for Mucosal Vaccine Delivery:R. Curtiss III, Attenuated Salmonella as Vectors for Oral Immunization.J. Ulmer, Current View of DNA Immunization for Mucosal Vaccines.S. Langermann, Recombinant BCG as Vector for Mucosal Immunity.C. Morrow, Recombinant Polio as Mucosal Vector.K. Rosenthal, Recombinant Adenovirus as Vector for Mucosal Immunity.R. Gilley, Current View of Microspheres as Mucosal Antigen Delivery System.M. Tomasi, ISCOMS, Liposomes and Oil Based Delivery Systems.S. Hamada and Y. Kodama, Application of Passive Immunity for Mucosal Vaccination.Mucosal Vaccines for Bacterial Diseases:M.R. Levine and M. Sztein, Human Mucosal Vaccines for Salmonella typhi Infection.A.A. Lindberg and T. Pal, Oral Vaccine for Shigella.J.J. Mekalanos, Live, Attenuated Cholera Vaccine.J.R. Holmgren and A.-M. Svennerholm, Oral Cholera and Enterotoxigenic E. coli Vaccines.P.B. Ernst and S. Czinn, Mucosal Immunity to Helicobacter pylori.D. Hoft, Oral BCG.Mucosal Vaccines for Viral Diseases:P.L. Ogra, Polio Viruses and Mucosal Vaccines.P.F. Wright, Mucosal RSV Vaccines.R.B. Couch, Mucosal Influenza Vaccines.R.B. Belshe, Mucosal Parainfluenza Vaccine.M. Conner, M.K. Estes, H. Greenberg, P. Offit, and H.F. Clark, Development of a Mucosal Rotaviros Vaccine.A.Z. Kapikian, Rotavirus Vaccines--The Clinical Experience.C. Miller and T. Lehner, Rectal and Vaginal Immunization for HIV/SIV.Site-Directed Mucsal Vaccine:C. Wira, Mucosal Immunity in the Female Reproductive System.C. Svanborg, Mucosal Immunity in the Urinary System.P. Montgomery and J. Whittum-Hudson, Mucosal Immunity in the Ocular System.S. Tamura and T. Kurata, Intranasal Immunization with Influenza Vaccine.R.J. Genco and R.C. Page, Mucosal Immunity for Oral Diseases.D.J. Lim and G. Morg, Mucosal Immunity in the Middle Ear.Subject Index.


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