Molecular Tools and Infectious Disease Epidemiology


  • Betsy Foxman, Professor of Epidemiology, University of Michigan School of Public Health; Director, Center for Molecular and Clinical Epidemiology of Infectious Diseases, Ann Arbor, MI, USA

The application of modern molecular genetic and biologic techniques to infectious disease epidemiology dramatically improves measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. We examine these opportunities and methodologic challenges giving specific examples. The book will be written for the reader with limited understanding of genetics, biology and epidemiology.
View full description


Graduate and advanced undergraduate students studying infectious disease epidemiology, molecular epidemiology, the epidemiologist wishing to integrate molecular techniques into his or her studies


Book information

  • Published: January 2011
  • ISBN: 978-0-12-374133-2

Table of Contents

Chapter 1. Introduction and Historical Perspective
Chapter 2. How Molecular Tools Enhance Epidemiologic Studies
Chapter 3. Applications of Molecular Tools to Infectious Disease Epidemiology
Chapter 4. A Primer of Epidemiologic Study Designs
Chapter 5. A Primer of Molecular Biology
Chapter 6. Molecular Tools
Chapter 7. Omics Analyses in Molecular Epidemiologic Studies
Chapter 8. Determining the Reliability and Validity and Interpretation of a Measure in the Study Populations
Chapter 9. Designing and Implementing a Molecular Epidemiologic Study
Chapter 10. Study Conduct

Chapter 11. Think About Data Analysis When Planning a Study
Chapter 12. Human and Animal Subject Protection, Biorepositories, Biosafety Considerations, and Professional Ethics
Chapter 13 Future Directions