Molecular Pathology of Pituitary Adenomas

By

  • Cristiana Tanase, Victor Babes National Institute of Pathology, Bucharest, Romania
  • Irina Ogrezeanu, "D. Bagdasar" Hospital, Bucharest, Romania
  • Corin Badiu, "C.Davila" University of Medicine and Pharmacy and Institute of Endocrinology, Bucharest, Romania

The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research.

This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies.

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Audience

Pathologists, clinical endocrinologists, neurosurgeons, basic scientists

 

Book information

  • Published: November 2011
  • Imprint: ELSEVIER
  • ISBN: 978-0-12-415830-6


Table of Contents

1. Pituitary tumor classification: functionality, invasiveness, aggressiveness

Irina Ogrezeanu, Corin Badiu, Cristiana Tanase, Alina Neagoe

2. Immunohistochemistry and electron microscopy as evaluation criteria in tumour classification in the deciphering of pituitary adenomas

Corin Badiu, Irina Ogrezeanu, Cristiana Tanase

3. Proliferation

Cristiana Tanase and Radu Albulescu

4. Angiogenesis

Cristiana Tanase, Elena Codrici, Irina Radu, Simona Mihai

5. Apoptosis

Cristiana Tanase, Radu Albulescu

6. Signal transduction

Cristiana Tanase, Monica Neagu, Radu Albulescu, Linda Maria Cruceru, Adrian Popa

7. Stem cells markers in pituitary adenomas

Corin Badiu, Cristiana Tanase, Linda Maria Cruceru

8. microRNAs

Cristiana Tanase, Radu Albulescu, Lucian Albulescu

9. New generic tools for diagnosis: genomics, proteomics

Cristiana Tanase, Radu Albulescu, Ionela Daniela Popescu

10. Therapeutic approach: drug, surgical and radiotherapy

Cristiana Tanase, Irina Ogrezeanu