Molecular Biology
By- David Clark, BA (honors)Christ's College Cambridge, 1973 PhD University of Brsitol (England), 1977, Southern Illinois University, Carbondale, Illinois, USA
- Nanette Pazdernik, School of Medicine at Washington University, St. Louis, Missouri, USA
The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. This book reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community.
Audience
Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture
Hardbound, 928 Pages
Published: February 2012
Imprint:
ISBN: 978-0-12-378594-7
Reviews
-
"This comprehensive text gives students and researchers a sound and practical knowledge of molecular biology. Consisting of 28 lucidly written chapters, this book presents basic concepts, recent updates, methodological principles and applications in this central biology discipline. The authors have adopted an interesting pedagogic approach to ensure smooth delivery of the presented information. This involved the use of nicely-designed meaningful illustrations, highlighting key concepts in each chapter, and raising review and conceptual questions. There is also a novel feature of Focus on Relevant Research sections relating pertinent research articles to key concepts in the text. These sections illustrate how the development of frontier research in molecular biology is based upon the proper understanding of its prime concepts. This second edition of the text is accompanied by an online study guide, which contains useful material including review questions, and references to relevant articles. I would highly recommend this informative, well-presented book to students and researchers seeking sound and practical updated knowledge in molecular biology."-- Science Progress
Contents
Unit 1: Basic Chemical and Biological Principles
Ch1 Cells and Organisms
Ch2 Basic Genetics
Ch3 DNA, RNA, and ProteinCh4 Genes, Genomes, and DNA
Ch5 Manipulation of Nucleic AcidsUnit 2: The Genome
Ch6 Polymerase Chain ReactionCh7 Cloning Genes for Analysis
Ch8 DNA SequencingCh9 Genomics & Systems Biology
Unit 3: The Central Dogma of Molecular BiologyCh10 Cell Division and DNA Replication
Ch11 Transcription of GenesCh12 Processing of RNA
Ch13 Protein SynthesisCh14 Protein Structure & Function
Ch15 Proteomics: Global Analysis of ProteinsUnit 4: Regulating Gene Expression
Ch16 Regulation of Transcription in ProkaryotesCh17 Regulation of Transcription in Eukaryotes
Ch18 Regulation at RNA LevelCh19 Analysis of Gene Expression (Transcriptome)
Unit 5: Subcellular Life FormsCh20 Plasmids
Ch21 VirusesCh22 Mobile DNA
Unit 6: Changing the DNA BlueprintCh23 Mutations and Repair
Ch24 RecombinationCh25 Bacterial Genetics
Ch26 Molecular Evolution
