Molecular Biology book cover

Molecular Biology

The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. The second edition of Molecular Biology, winner of a 2013 Texty Award from the Text and Academic Authors Association, reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. This volume effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community.

Audience

Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture

Hardbound, 928 Pages

Published: February 2012

Imprint:

ISBN: 978-0-12-378594-7

Reviews

  • "This molecular biology textbook from Clark and Pazdernik is geared toward upper-level undergraduate and beginning graduate students. The book is written with a preference for breadth over depth, beginning with several chapters to cover the basics for students with a non-molecular background in biology and continuing on in survey fashion to the topics of genomics research, RNA and protein function, gene expression, subcellular life-forms, and DNA alteration."--Reference & Research Book News, October 2013
    "This book reflects the massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves."--ANTICANCER RESEARCH 33: 745-746 (2013), February 2013
    "This comprehensive text gives students and researchers a sound and practical knowledge of molecular biology. Consisting of 28 lucidly written chapters, this book presents basic concepts, recent updates, methodological principles and applications in this central biology discipline. The authors have adopted an interesting pedagogic approach to ensure smooth delivery of the presented information. This involved the use of nicely-designed meaningful illustrations, highlighting key concepts in each chapter, and raising review and conceptual questions. There is also a novel feature of ‘Focus on Relevant Research’ sections relating pertinent research articles to key concepts in the text. These sections illustrate how the development of frontier research in molecular biology is based upon the proper understanding of its prime concepts. This second edition of the text is accompanied by an online study guide, which contains useful material including review questions, and references to relevant articles. I would highly recommend this informative, well-presented book to students and researchers seeking sound and practical updated knowledge in molecular biology."--
    Science Progress


Contents

  • Unit 1: Basic Chemical and Biological Principles

    Ch1 Cells and Organisms

    Ch2 Basic Genetics

    Ch3 DNA, RNA, and Protein

    Ch4 Genes, Genomes, and DNA

    Ch5 Manipulation of Nucleic Acids

    Unit 2: The Genome

    Ch6 Polymerase Chain Reaction

    Ch7 Cloning Genes for Analysis

    Ch8 DNA Sequencing

    Ch9 Genomics & Systems Biology

    Unit 3: The Central Dogma of Molecular Biology

    Ch10 Cell Division and DNA Replication

    Ch11 Transcription of Genes

    Ch12 Processing of RNA

    Ch13 Protein Synthesis

    Ch14 Protein Structure & Function

    Ch15 Proteomics: Global Analysis of Proteins

    Unit 4: Regulating Gene Expression

    Ch16 Regulation of Transcription in Prokaryotes

    Ch17 Regulation of Transcription in Eukaryotes

    Ch18 Regulation at RNA Level

    Ch19 Analysis of Gene Expression (Transcriptome)

    Unit 5: Subcellular Life Forms

    Ch20 Plasmids

    Ch21 Viruses

    Ch22 Mobile DNA

    Unit 6: Changing the DNA Blueprint

    Ch23 Mutations and Repair

    Ch24 Recombination

    Ch25 Bacterial Genetics

    Ch26 Molecular Evolution

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