Molecular Basis of Memory

Edited by

  • E. Chris Muly, Emory University, Atlanta, USA
  • Zafar Khan, Universidad de Málaga, Spain

This special volume of Progress in Molecular Biology and Translational Science provides a current overview of how memory is processed in the brain. A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies.
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Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.


Book information

  • Published: February 2014
  • ISBN: 978-0-12-420170-5


"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--BRITISH MEDICAL JOURNAL

Table of Contents

  1. Memory Deficits in Aging and Neurological Diseases
    Zafar U. Khan, Elisa Martin-Montañez, Irene Navarro-Lobato and E. Chris Muly
  2. The “Memory Kinases”: Roles of PKC Isoforms in Signal Processing and Memory Formation
    Miao-Kun Sun and Daniel L. Alkon
  3. CaMKII: A Molecular Substrate for Synaptic Plasticity and Memory
    Brian C. Shonesy, Nidhi Jalan-Sakrikar, Victoria S. Cavener and Roger J. Colbran
  4. The Transcription Factor Zif268/Egr1, Brain Plasticity and Memory
    Alexandra Veyrac, Antoine Besnard, Jocelyne Caboche, Sabrina Davis and Serge Laroche
  5. Mechanisms of Translation Control Underlying Long-lasting Synaptic Plasticity and the Consolidation of Long-term Memory
    Emanuela Santini, Thu N. Huynh and Eric Klann
  6. BDNF - TrkB Receptor Regulation of Distributed Adult Neural Plasticity, Memory Formation, and Psychiatric Disorders
    Raül Andero, Dennis C. Choi and Kerry J. Ressler
  7. Mechanisms of Synaptic Plasticity and Recognition Memory in the Perirhinal Cortex
    Paul J. Banks, E. Clea Warburton, Malcolm W. Brown and Zafar I. Bashir
  8. Molecular Influences on Working Memory Circuits in Dorsolateral Prefrontal Cortex
    Amy F.T. Arnsten and Lu E. Jin
  9. Cost-Benefit Decision Circuitry: Proposed Modulatory Role for Acetylcholine
    Wambura C. Fobbs and Sheri J. Y. Mizumori
  10. Molecular Mechanisms of Threat Learning in the Lateral Nucleus of the Amygdala
    Robert M. Sears, Hillary C. Schiff and Joseph E. LeDoux
  11. Epigenetics of Memory and Plasticity
    Bisrat T. Woldemichael, Johannes Bohacek, Katharina Gapp and Isabelle M. Mansuy
  12. Deciphering Memory Function with Optogenetics
    Anna Beyeler, Christine A. Eckhardt and Kay M. Tye
  13. The Tagging and Capture Hypothesis from Synapse to Memory
    Haydée Viola, Fabricio Ballarini, María Cecilia Martínez and Diego Moncada