Models of Protection Against HIV/SIV
Avoiding AIDS in humans and monkeysEdited by
- Gianfranco Pancino
- Guido Silvestri
- Keith Fowke
The primary audience for this work is HIV/AIDS physicians, researchers and policy makers in academia, industry and government, as well as, medical and graduate students looking to further their understanding of HIV/AIDS vaccine efforts.
Hardbound, 360 Pages
Published: December 2011
Imprint: Academic Press
"Researchers in immunology, virology, microbiology, genetics, and other medical specialties from Europe and North America first overview the distribution and biological properties of primate lentiviruses and the emergence of HIV, including features of HIV-1 that distinguish it from HIV-2 and SIVs that replicate efficiently in African non-human primates without causing disease, and the development of these properties and their potential roles in the pathogenesis of AIDS. They then discuss immunological aspects of SIV in monkeys studied the most with respect to correlates of protection against AIDS, implications for therapy, whether some people are protected against infection, the genital mucosa in transmission, genetic factors contributing to resistance or susceptibility, the immune mechanisms that correlate with resistance, HIV controllers and viral factors involved, adaptive and immune responses associated with controllers, immune mechanisms of viral control in HIV-2 infection, and the genetic basis of protection."--Reference and Research Book News, Inc.