Minimized Cardiopulmonary Bypass Techniques and Technologies

Edited by

  • Terence Gourlay, University of Strathclyde, UK
  • Serdar Gunaydin, K. Kale University, Turkey

Traditional cardiopulmonary bypass (CPB) techniques have suffered from a number of disadvantages including haemodilution, inflammation and post-operative bleeding. Minimised cardiopulmonary bypass techniques use developments in perfusion technology to significantly reduce foreign surface-blood interactions to make bypass simpler and safer. This important book reviews key developments and issues relating to this promising technology.

Part one covers the broad range of CPB pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces, optimal haemodilution levels, and the important issue of CPB-induced systemic inflammatory response syndrome. Part two focuses on the issues of the new equipment developed for mini-CPB, optimal myocardial protection protocols and CPB perfusate options. Part three discusses clinical issues, including patient selection, coronary and valve surgery protocols and, among others, paediatric patients.

With its distinguished editors and international team of expert contributors, Minimized cardiopulmonary bypass techniques and technologies is a valuable reference for cardiac surgery teams and those researching this important technology.
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Clinicians, especially those concerned with cardiology.


Book information

  • Published: April 2012
  • Imprint: Woodhead Publishing
  • ISBN: 978-1-84569-800-3


The book is comprehensive in its scope and authoritative in the experience of its chapter authors. I commend the book to all members of cardiac surgery teams - surgeons, cardiologists, anaesthetists and perfusionists., Professor Ken Taylor, Emeritus Professor of Cardiac Surgery, Imperial College and The Hammersmith Hospital, London (from the Foreword)

Table of Contents

Part 1 Introduction to minimized cardiopulmonary bypass: Historical development of minimized cardiopulmonary bypass; Anticoagulation protocols for minimized cardiopulmonary bypass; Minimized extracorporeal circulation: Physiology and pathophysiology; Blood-surface interface in miniatururised extracorporeal circulation systems; Hemodilution: Physiology and pathophysiology; Inflammatory response and minimized cardiopulmonary bypass. Part 2 Minimized cardiopulmonary bypass equipment: Design and principles of the minimized extracorporeal circuit; Cardiopulmonary bypass perfusate; Myocardial preservation techniques for mini-bypass. Part 3 Clinical applications of minimized cardiopulmonary bypasses: Minimized cardiopulmonary bypass: Objectives and indications; Coronary artery bypass grafting (CABG); Valve surgery using minimized perfusion circuits; Minimising cardiopulmonary bypass in children; Comparison of minimized circulation with off-pump coronary artery bypass grafting (OPCAB) and conventional surgery; Minimally invasive cardiac surgery, port-access and robotic surgery.