Microfluidic Devices for Biomedical Applications

Edited by

  • Xiujun James Li
  • Yu Zhou, Genus Plc, USA

Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.

The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.

Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.
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Medical device manufacturers, scientists, and researchers concerned with microfluidics in the field of drug delivery, cell manipulation, tissue engineering and diagnostics/sensing; Industrial and academic researchers and developers in the life sciences and engineering fields who aim to use microengineering technologies to develop advanced techniques and microdevices for advancements in healthcare and medical diagnostics


Book information

  • Published: October 2013
  • Imprint: Woodhead Publishing
  • ISBN: 978-0-85709-697-5


"Mechanical and biomedical engineers, chemists, and other contributors briefly introduce the fundamentals of microfluidics, then survey current research into microfluidic devices or lab-on-chip platforms in biomedical applications. Among the topics are: surface coatings for microfluidic-based biomedical devices, actuation mechanisms,…"--ProtoView.com, March 2014

Table of Contents

Part 1 Fundamentals of microfluidic technologies for biomedical applications: Materials and methods for the microfabrication of microfluidic biomedical devices; Surface coatings for microfluidic-based biomedical devices; Actuation mechanisms for microfluidic biomedical devices; Digital microfluidics technologies for biomedical devices. Part 2 Applications of microfluidic devices for drug delivery and discovery: Controlled drug delivery using microfluidic devices; Microneedles for drug delivery applications; Microfluidic devices for drug discovery and analysis. Part 3 Applications of microfluidic devices for cellular analysis and tissue engineering: Microfluidic devices for cell manipulation; Microfluidic devices for automated micro-robotic cell injection and trapping; Microfluidic devices for developing tissue scaffolds; Microfluidic devices for stem cell analysis. Part 4 Applications of microfluidic devices in diagnostic sensing: Development of immunoassays for protein analysis on nanobioarray chips; Integrated microfluidic systems for genetic analysis; Low-cost assays in paper-based microfluidic biomedical devices; Microfluidic devices for viral detection; Microfluidics for monitoring and imaging pancreatic islets and ?-cells; Microfluidic devices for radio chemical synthesis.