Metal Transporters
Edited by- Jose Arguello, Worcester Polytechnic Institute
- Svetlana Lutsenko, Professor of Physiology Johns Hopkins University
This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others.
Audience
Researchers in biochemistry, molecular and cellular biology.
Hardbound, 456 Pages
Published: October 2012
Imprint: Academic Press
ISBN: 978-0-12-394390-3
Contents
- Regulation of Copper Transporters in Human Cells
- Transferrin Mediated Cellular Iron Delivery
- Structure, Function and Binding Selectivity and Stereoselectivity of Siderophore-Iron Outer Membrane Transporters
- Iron Transport Machinery of Human Cells: Players and their Interactions
- Structure and Function of Copper Uptake Transporters
- Toward a Molecular Understanding of Metal Transport by P
1B -Type ATPases - Metal Export by CusCFBA, the Periplasmic Cu(I)/Ag(I) Transport System of
E. coli Tiffany D. Mealman, Ninian J. Blackburn and Megan M. McEvoy - Molecular Architecture and Function of ZnT Transporters
- The Cation Selectivity of the ZIP Transporters
- Nramp: from Sequence to Structure and Mechanism of Divalent Metal Import
- Genetic and Biochemical Approaches for Studying the Yellow Stripe-Like (YSL) Transporter Family in Plants
- Pathways of Arsenic Uptake and Efflux Hung-Chi Yang, Hsueh-Liang Fu , Yung-Feng Lin and Barry P. Rosen
- Extra Heme Uptake and the Challenges of Bacterial Cell Membranes
- The Mechanisms of Mg 2+ and Co 2+ Transport by the CorA Family of Divalent Cation Transporters
Nesrin M. Hasan and Svetlana Lutsenko Ashley N. Steere and Anne B. Mason Isabelle J. Schalk, Gaëtan L. A. Mislin and Karl Brillet Ningning Zhao and Caroline A. Enns Christopher R Pope, Adrian G Flores, Jack H Kaplan and Vinzenz M Unger Amy C. Rosenzweig and José M. Argüello Taiho Kambe Robert E. Dempski Mathieu FM. Cellier Sarah S. Conte and Elsbeth L. Walker Aaron D. Smith and Angela Wilks Albert Guskov and Said Eshaghi

