Memory Loss

A Practical Guide for Clinicians

By

  • Andrew Budson, MD, Neurology Service, Section of Cognitive & Behavioral Neurology, Veterans Affairs Boston Healthcare System, Boston, MA; Alzheimer's Disease Center & Department of Neurology, Boston University School of Medicine, Boston, MA; Harvard Medical School, Boston, MA; The Boston Center for Memory, Newton, MA; The Memory Clinic, Bennington, VT
  • Andrew Budson, MD, Neurology Service, Section of Cognitive & Behavioral Neurology, Veterans Affairs Boston Healthcare System, Boston, MA; Alzheimer's Disease Center & Department of Neurology, Boston University School of Medicine, Boston, MA; Harvard Medical School, Boston, MA; The Boston Center for Memory, Newton, MA; The Memory Clinic, Bennington, VT
  • Paul Solomon, PhD, Department of Psychology, Program in Neuroscience, Williams College, Williamstown, MA; The Boston Center for Memory, Newton, MA; The Memory Clinic, Bennington, VT
  • Paul Solomon, PhD, Department of Psychology, Program in Neuroscience, Williams College, Williamstown, MA; The Boston Center for Memory, Newton, MA; The Memory Clinic, Bennington, VT

Memory Loss combines expert guidance, case studies, and diagnostic tests to help you effectively diagnose Alzheimer’s disease and other common dementias. Drs. Andrew E. Budson and Paul R. Solomon cover the essentials of physical and cognitive examinations, laboratory and imaging studies, and the latest treatment approaches. The practical text, diagnostic tests, and online access to a downloadable image bank at www.expertconsult.com are the tools you need to consistently make accurate diagnoses.
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Book information

  • Published: June 2011
  • Imprint: SAUNDERS
  • ISBN: 978-1-4160-3597-8

Reviews

The cohesive text is an appealing blend of personal experience and clinical anecdotes, and is supported by a firm command of the rapidly changing clinical literature. The writing is crisp, lucid and, above all, practice-oriented … Budson and Solomon are especially adroit in identification of controversies, knowledge gaps, and areas in which diagnostic criteria are ill-defined or difficult to apply (eg, fluctuating cognition in dementia with Lewy bodies). Readers are not abandoned without guidance; ambiguities are resolved by confident descriptions of personal approaches to specific situations … The book is an incredible compilation of practical advice. (Lancet Neurology, March 2012)

"From the point of view of the busy clinician working in the trenches but looking for a practical and cutting-edge guide, Doraiswamy said he cannot think of a better book, noting, ‘This is the clinical book of the year in our field.’" (Alzheimer's Research Forum review, December 2011)

"Few books provide both a comprehensive review and a step-by-step guide. I strongly recommend this book to all those who treat patients with memory loss-physicians, social workers, psychologists, nurses-at every level of training and experience." - P. Murali Doraiswamy, M.D.(Professor & Head, Division of Biological Psychiatry, Duke University, and co-author of The Alzheimer’s Action Plan)

"Memory Loss: A Practical Guide for Clinicians provides the assessment, diagnostic and therapeutic insights clinicians need to provide exemplary care to memory impaired patients. Don’t go to the clinic without it." - Jeffrey L. Cummings, M.D. (Director, Cleveland Clinic Lou Ruvo Center for Brain Health, The Andrea L. and Joseph F. Hahn MD Chair of Neurotherapeutics)

"Designed for easy reference to satisfy the real time needs of clinicians in hectic clinical settings, I’m sure this volume will be dog-eared in short order given its clear no-nonsense style." - Neil W. Kowall, M.D. (Professor of Neurology and Pathology, Boston University School of Medicine, Director, Boston University Alzheimer’s Disease Center,Chief, Neurology Service, Boston VA Healthcare System)

"This book summarizes complex material in a manner that benefits clinical practitioners at all levels. This is an excellent addition to the library of professionals serving older adults." - Maureen K. O’Connor, (Psy.D., ABCN, Chief, Neuropsychology Service, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA)

"This is a very good addition to the books on dementias. With this book, the authors provide a resource for clinicians who will be caring for the more than 5 million individuals with memory loss, whether their degree is in medicine, psychology, nursing, social work, or therapies. Primary care providers, nurses, psychologists, and students will find this book a very practical, clinically oriented guide that helps them know what to do when sitting in the office with a patient complaining of memory loss. Specialists will find this book a wealth of up-to-date information regarding the latest diagnostic tools and treatments for their patients with memory loss."

- Eric Gausche, MD, University of Illinois at Chicago College of Medicine

4 Star- Doody Rating, March 2013




Table of Contents

SECTION I EVALUATING THE PATIENT WITH MEMORY LOSS

CHAPTER 1 Why Diagnose and Treat?...................................................................1

CHAPTER 2 Evaluating the Patient with Memory Loss ............................................4

SECTION II DIFFERENTIAL DIAGNOSIS OF MEMORY LOSS

CHAPTER 3 Alzheimer’s Disease.........................................................................43

CHAPTER 4 Mild Cognitive Impairment ...............................................................71

CHAPTER 5 Dementia with Lewy Bodies (Including Parkinson’s

Disease Dementia) ...........................................................................79

CHAPTER 6 Vascular Dementia and Vascular Cognitive

Impairment ......................................................................................91

CHAPTER 7 Frontotemporal Dementia................................................................104

CHAPTER 8 Progressive Supranuclear Palsy .....................................................118

CHAPTER 9 Corticobasal Degeneration .............................................................128

CHAPTER 10 Normal Pressure Hydrocephalus.....................................................136

CHAPTER 11 Creutzfeldt-Jakob Disease..............................................................143

CHAPTER 12 Other Disorders..............................................................................148

SECTION III TREATMENT OF MEMORY LOSS

CHAPTER 13 Goals of Treatment.........................................................................163

CHAPTER 14 Cholinesterase Inhibitors................................................................166

CHAPTER 15 Memantine (Namenda) ...................................................................184

CHAPTER 16 Vitamins, Herbs, Supplements, and Anti-Inflammatories...................193

CHAPTER 17 Future Treatments of Memory Loss .................................................199

CHAPTER 18 Non-Pharmacological Treatment of Memory Loss ............................214

SECTION IV BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS

OF DEMENTIA

CHAPTER 19 Evaluating the Behavioral and Psychological

Symptoms of Dementia...................................................................220

CHAPTER 20 Caring for and Educating the Caregiver...........................................228

CHAPTER 21 Non-Pharmacological Treatment of the Behavioral and

Psychological Symptoms of Dementia .............................................236

CHAPTER 22 Pharmacological Treatment of the Behavioral and Psychological

Symptoms of Dementia...................................................................247

SECTION V ADDITIONAL ISSUES

CHAPTER 23 Life Adjustments ............................................................................259

CHAPTER 24 Legal and Financial Issues.............................................................266

CHAPTER 25 Special Issues...............................................................................271

SECTION VI CASE STUDIES..............................................275

ONLINE ONLY APPENDICES: (See inside front cover for details)

APPENDIX A Cognitive Test and Questionnaire Forms, Instructions,

and Normative Data

APPENDIX B Screening for Memory Loss

APPENDIX C Our Current Understanding of Memory

Index.....................................................................................................................289