Membrane Proteins as Drug Targets book cover

Membrane Proteins as Drug Targets

Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to new and improved pharmaceutical treatments for a wide range of illnesses such as heart disease, cystic fibrosis and depression.

This volume reviews the latest developments in the field.


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Hardbound, 270 Pages

Published: August 2010

Imprint: Academic Press

ISBN: 978-0-12-381288-9


    "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal


    1. Inverse Agonism at Serotonin and Cannabinoid Receptors

             Vincent J. Aloyo, Kelly A. Berg, William P. Clarke, Umberto Spampinato, and John A. Harvey

      2.    G protein-coupled receptor heteromers as new targets for drug development

        Sergi Ferré, Gemma Navarro, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carme Lluís and Rafael Franco

      3.    Receptor activity modifying proteins and their potential as drug targets

        Denise L. Wootten, John Simms, Debbie L. Hay, Arthur Christopoulos and Patrick M. Sexto

        4.  Regulators of G Protein Signaling Proteins As Targets For Drug Discovery

        Benita Sjögren, Levi L. Blazer and Richard R. Neubig

      5.    Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets

        Dumaine Williams and Lakshmi A. Dev

        6.    The T1r2/T1r3 Sweet Receptor and Trpm5 Ion Channel: Taste Targets With Therapeutic Potential

        Dennis Sprous and R. Kyle Palmer

        7.     Membrane-associated enzymatic synthesis

        Edward A. Esposito and Robert Weis


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