Medicinal Chemistry of Anticancer DrugsBy
- Carmen Avendano
- J. Carlos Menendez
Researchers involved in oncology and pharmaceutical, medicinal and organic chemistry; Practitioners; Advanced undergraduate and graduate students in medicinal chemistry and pharmacology.
Hardbound, 400 Pages
Published: April 2008
- Introduction to anticancer chemotherapy; Antimetabolites; Anticancer drugs that inhibit hormone action; Anticancer drugs acting via radical species. Photosensitizers and photodynamic therapy of cancer; DNA alkylating agents; Alkylating and non-alkylating compounds interacting with the DNA minor groove; DNA intercalation and inhibition of topoisomerases; Anticancer drugs targeting tubulin and microtubules; Drugs targeting signaling pathways for tumour cell growth and proliferation; Other approaches to targeted therapy; Drug targeting in anticancer chemotherapy; Resistance to antitumour agents and drugs that modulate it; Cancer chemoprevention.