Mechanisms of DNA Repair

Written by research experts, this volume of Progress in Molecular Biology and Translational Science focuses on current science surrounding the mechanisms of DNA repair.
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Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.


Book information

  • Published: July 2012
  • ISBN: 978-0-12-387665-2


"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal

Table of Contents

  1. Dynamics of Lesion Processing by Bacterial Nucleotide Excision Repair Proteins
    Neil M. Kad and Bennett Van Houten
  2. Transcription-coupled DNA Repair in Prokaryotes
    Ann Ganesan, Graciela Spivak, and Philip C. Hanawalt
  3. The Functions of MutL in Mismatch Repair: The Power of Multitasking
    Alba Guarné
  4. The Fpg/Nei Family of DNA Glycosylases: Substrates, Structures and Search for Damage
    Aishwarya Prakash, Sylvie Doublié and Susan S. Wallace
  5. Regulation of Base Excision Repair in Eukaryotes by Dynamic Localization Strategies
    Swartzlander DB, Bauer NC, Corbett AH and Doetsch PW
  6. Oxidized Base Damage and Single-Strand Break Repair in Mammalian Genomes: Role of Disordered Regions and Posttranslational Modifications in Early Enzymes
    Muralidhar L. Hegde, Tadahide Izumi and Sankar Mitra
  7. Homologous Recombination in Eukaryotes
    Ravindra Amunugama and Richard Fishel
  8. Overview for the Histone Codes for DNA Repair
    Elizabeth A. Williamson, Justin W. Wray, Pranshu Bansal and Robert Hromas
  9. The RSC and INO80 Chromatin Remodeling Complexes in DNA Double-Strand Break Repair
    Anna L. Chambers and Jessica A. Downs
  10. Mechanistic Links between ATM and Histone Methylation Codes during DNA Repair
    Ye Xu, Chang Xu and Brendan D. Price
  11. Exploiting Synthetic Lethal Interactions between DNA Damage Signaling, Checkpoint Control and p53 for Targeted Cancer Therapy
    Sandra Morandell and Michael B. Yaffe