Mechanisms and Pathways of Heterotrimeric G Protein Signaling

Stephen Sprang, University of Texas Southwestern Medical Center, Dallas, Texas, USA

Audience
Researchers in biochemistry, molecular biology, cell biology, and biophysics.

Included in series
Advances in Protein Chemistry and Structural Biology

Hardbound, 290 Pages

Published: October 2007

Imprint: Academic Press

ISBN: 978-0-12-034288-4

1. Structural basis of effector regulation and signal termination in heterotrimeric GÑnnproteinsStephen R. Sprang, Zhe Chen and Xinlin Du2. How do receptors activate G proteins?William M. Oldham and Heidi E. Hamm3. Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beadsTione Buranda, Anna Waller, Yang Wu, Peter C. Simons, Sean Biggs, Eric R. Prossnitz and Larry A. Sklar4. Activation of G protein coupled receptorsXavier Deupi and Brian Kobilka5. Kinetic analysis of g-protein-coupled receptor signaling using fluorescence resonance energy transfer in living cellsMartin J. Lohse, Carsten Hoffmann, Viacheslav O. Nikolaev, Jean-Pierre Vilardaga and Moritz Bunemann6. Regulation of Rho Guanine Nucleotide Exchange Factors (RhoGEFs) by G proteinsPaul C. Sternweis, Angela M. Carter, Zhe Chen, Shahab M. Danesh, Ying-Fan Hsiung, and William D. Singe

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