Mechanisms and Models in Rheumatoid Arthritis

Edited By

  • B. Henderson, Eastman Dental Institute and University College London Hospitals, U.K.
  • J. Edwards
  • E. Pettipher, Pfizer Inc., Groton, Connecticut, U.S.A.


Book information

  • Published: March 1995
  • ISBN: 978-0-12-340440-4

Table of Contents

Cellular Mechanims in Rheumatoid Arthritis: Histopathology of Rheumatoid Joint. Pannus. Synovial Cells. Bone Cells and Bone Remodelling in Rheumatoid Arthritis. T Lymphocyte/Macrophage Interactions. Leukocyte Adhesion and Leukocyte Traffic in Rheumatoid Arthritis. Humoral Mechanisms in Rheumatoid Arthritis.: Inflammatory Cytokines Including the IL-8 Supergene Family. Cytokine Inhibitors, Growth Factors. Lipid Mediators. Oxidants/Free Radicals. Neuropeptides. Proteases and Connective Tissue Breakdown. Animal Models of Rheumatoid Arthritis: Role of Animal Models in the Study of Rheumatoid Arthritis: A General Review. Immunogenerics of Animal Models of Rheumatoid Arthritis. Adjuvant Arthritis: The First Model? Arthritis Induced By Bacteria and Viruses. Streptococcal Cell Wall Arthritis. Collagen-Induced Arthritis. Antigen-Induced Arthritis in Rodents. Antigen-Induced Arthritis in the Rabbit. Animal Models of Rheumatoid Arthritis. Spontaneous Arthritis Models. Cytokine-Induced Arthritis. Animal Models and Anti-Rheumatic Drug Development.