Mathematics for Neuroscientists

By
  • Fabrizio Gabbiani
  • Fabrizio Gabbiani
  • Steven Cox
  • Steven Cox

This book provides a grounded introduction to the fundamental concepts of mathematics, neuroscience and their combined use, thus providing the reader with a springboard to cutting-edge research topics and fostering a tighter integration of mathematics and neuroscience for future generations of students.

The book alternates between mathematical chapters, introducing important concepts and numerical methods, and neurobiological chapters, applying these concepts and methods to specific topics. It covers topics ranging from classical cellular biophysics and proceeding up to systems level neuroscience. Starting at an introductory mathematical level, presuming no more than calculus through elementary differential equations, the level will build up as increasingly complex techniques are introduced and combined with earlier ones. Each chapter includes a comprehensive series of exercises with solutions, taken from the set developed by the authors in their course lectures. MATLAB code is included for each computational figure, to allow the reader to reproduce them. Biographical notes referring the reader to more specialized literature and additional mathematical material that may be needed either to deepen the reader's understanding or to introduce basic concepts for less mathematically inclined readers completes each chapter.

Audience
* Graduate and post graduate students in Neuroscience and Psychology looking for an introduction to mathematical methods in Neuroscience
* Researchers in Neuroscience and Psychology looking for a quick reference for mathematical methods
* Students in applied mathematics, physical sciences, engineering who want an introduction to Neuroscience in a mathematical context

Hardbound, 498 Pages

Published: July 2010

Imprint: Academic Press

ISBN: 978-0-12-374882-9

Reviews

  • "Mathematics for Neuroscientists by Fabrizio Gabbiani and Steven Cox (GC) was developed over 8 years of teaching courses on the topic. This experience, as well as the wide-ranging research contributions of the authors, clearly shines through-the text is a landmark for the field in its scope, rigor, and accessibility. . . .This is a hallmark of the book: elegance, completeness, and economy that leave the reader with much more mathematics and science than one might expect even in a work of this size. The book further benefits from the availability of MATLAB code provided to regenerate almost every figure. . . . This integration of code and text is by far the best we’ ve seen. It brings alive the science, the mathematical tools, the models, and their implementation."-Society for Industrial and Applied Mathematics SIAM Review, 2011 (Vol 53, No. 3)


Contents

  • 1 Introduction
    2 The Passive Isopotential Cell
    3 Differential Equations
    4 The Active Isopotential Cell
    5 The Quasi-Active Isopotential Cell
    6 The Passive Cable
    7 Fourier Series and Transforms
    8 The Passive Dendritic Tree
    9 The Active Dendritic Tree
    10 Reduced Single Neuron Models
    11 Probability and Random Variables
    12 Synaptic Transmission and Quantal Release
    13 Neuronal Calcium Signaling
    14 The Singular Value Decomposition and Applications
    15 Quantification of Spike Train Variability
    16 Stochastic Processes
    17 Membrane Noise
    18 Power and Cross Spectra
    19 Natural Light Signals and Phototransduction
    20 Firing Rate Codes and Early Vision
    21 Models of Simple and Complex Cells
    22 Stochastic Estimation Theory
    23 Reverse-Correlation and Spike Train Decoding
    24 Signal Detection Theory
    25 Relating Neuronal Responses and Psychophysics
    26 Population Codes
    27 Neuronal Networks
    28 Solutions to Selected Exercises

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