Lipidomics and Bioactive Lipids: Specialized Analytical Methods and Lipids in Disease book cover

Lipidomics and Bioactive Lipids: Specialized Analytical Methods and Lipids in Disease

This volume in the well-established Methods in Enzymology series features methods for the study of lipids using mass spectrometry techniques. Articles in this volume cover topics such as Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosis; Measurement of eicosanoids in cancer tissues; Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular HealthA Detailed HPLC/MS/MS Method; Lipidomics in Diabetes and the Metabolic Syndrome; LC-MS-MS Analysis of Neutral Eicosanoids; Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant Stress; Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and Neurofurans; Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography; Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS); Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition Control; Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS); Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass Spectrometry.

Audience
Graduate students, researchers in academics and industry studying biochemistry.

Included in series
Methods in Enzymology

Hardbound, 296 Pages

Published: November 2007

Imprint: Academic Press

ISBN: 978-0-12-373966-7

Contents

  • Chapter 1Liquid chromatography mass spectrometry for quantifying plasma lysophospholipids: potential biomarkers for cancer diagnosisMandi Murph, Tamotsu Tanaka, Jihai Pang, Edward Felix, Shuying Liu, Rosanne Trost, Andrew K. Godwin, Robert Newman and Gordon MillsChapter 2Measurement of eicosanoids in cancer tissuesDingzhi Wang and Raymond N. DuBoisChapter 3Noninvasive Assessment of the Role of Cyclooxygenases in Cardiovascular HealthA Detailed HPLC/MS/MS MethodWen-Liang Song, John A. Lawson, Helen Zou, and Garret A. FitzGeraldChapter 4Lipidomics in Diabetes and the Metabolic SyndromeRichard W. Gross, Xianlin HanChapter 5LC-MS-MS Analysis of Neutral EicosanoidsPhilip J. Kingsley and Lawrence J. MarnettChapter 6Quantification Of F2-Isoprostanes In Biological Fluids And Tissues As A Measure Of Oxidant StressGinger L. Milne, Huiyong Yin, Joshua D. Brooks, Stephanie Sanchez, L. Jackson Roberts, II, and Jason D. MorrowChapter 7Measurement of Products of Docosahexaenoic Acid Peroxidation, Neuroprostanes, and NeurofuransKyle O. Arneson and L. Jackson Roberts, II.Chapter 8Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatographyClaus Schneider, Zheyong Yu, William E. Boeglin, Yuxiang Zheng, and Alan R. BrashChapter 9Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS)Seon Hwa Lee and Ian A. BlairChapter 10Shotgun Lipidomics by Tandem Mass Spectrometry under Data-Dependent Acquisition ControlDominik Schwudke, Gerhard Liebisch, Ronny Herzog, Gerd Schmitz and Andrej ShevchenkoChapter 11Identification of Intact Lipid Peroxides by Ag+ Coordination Ionspray Mass Spectrometry (CIS-MS)Huiyong Yin and Ned A. PorterChapter 12 Quantification of Cardiolipin by Liquid Chromatography Electrospray Ionization Mass SpectrometryTeresa A. Garrett*, Reza Kordestani, Christian R. H. Raetz

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