Lead Molecules from Natural Products

Discovery and New Trends

Edited by

  • Mahmud Tareq Hassan Khan, International Center for Chemical Sciences, University of Karachi, Pakistan
  • Arjumand Ather, The Norwegian Structural Biology Centre, University of Tromso, Norway

Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered.The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations.
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Phytochemists; Combinatorial Chemists; Pharmacologists; Scientists engaged in Drug discovery and development; Industrial research groups developing drugs from plants; Departments of pharmaceutics; Institutes for Drug Research; Pharmaceutical companies; Manufacturers of herbal and ayurvedic medicines and cosmetic productsManufacturers of natural products


Book information

  • Published: July 2006
  • Imprint: ELSEVIER
  • ISBN: 978-0-444-51619-0

Table of Contents

Reverse Pharmacognosy: a new concept for accelerating natural drug discoveryQuoc-Tuan DO and Philippe BERNARDEffects of Plant Extracts on Gene Expression Profiling: from Macrorrays to Microarray TechnologyCarlo Mischiati, Alessia Sereni, Mahmud Tareq Hassan Khan, Ilaria Lampronti and Roberto GambariEffects of Medicinal Plant Extracts on Molecular Interactions between DNA and Transcription FactorsIlaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Giordana Feriotto1, Carlo Mischiati, Monica Borgatti and Roberto GambariPlants with Antitumor Properties: from Biologically Active Molecules to DrugsIlaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Elisabetta Lambertini, Roberta Piva, Monica Borgatti and Roberto GambariHerbal Extracts and Compounds Active against Herpes Simplex VirusKenneth D. ThompsonCough and its Pharmacological ModulationNosalova, G., Mokry, J., Franova, SPhytotherapy of the CoughFranova, S., Nosalova G., Mokry, J.The Medicinal Potential of Black seed (Nigella sativa) and its ComponentsHala Gali-Muhtasib, Regine Schneider-StockCyclin Dependent Kinase Inhibitors from Natural Sources: Recent Advances and Future Prospects for Cancer TreatmentHala Gali-MuhtasibAnticancer and Medicinal Properties of Essential Oil and Extracts of East Mediterranean Sage (Salvia triloba)Hala Gali-MuhtasibMarine Organisms from Brazil as Source of Potential Anticancer AgentsLetícia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete A. Moraes, Adaíla Marta Paixão Almeida, Manoel Odorico de Moraes, Tito Monteiro da Cruz LotufoAnticancer Potential of Northeast Brazilian PlantsCláudia Pessoa, Letícia Veras Costa-Lotufo, Albert Leyva, Maria Elisabete Amaral de Moraes, Manoel Odorico MoraesSafety and Efficacy of PhytomedicinesManoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Letícia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete Amaral de MoraesPharmacological and Biochemical Profiling of Lead Compounds from Traditional Remedies: the case of Croton cajucaraMaria Aparecida M. Maciel, Tereza Neuma C. Dantas, Angelo C. Pinto, Valdir F. Veiga Jr., Carlos R. Kaiser, Nuno A. Pereira, Cristina M. T. S. Carneiro, Frederico A. Vanderlinde, Antônio J. Lapa, Aniele R. Agner, Ilce M. S. Cólus, Juliana Echevarria-Lima, Noema F. Grynberg, Andressa Esteves-Souza, Kenia Pissinate, Aurea EchevarriaAntihypertensive Peptides from Natural ResourcesToshiro Matsui, Kiyoshi MatsumotoXanthones As Therapeutic Agents: Chemistry And PharmacologyNoungoue Tchamo Diderot, Ngouela Silvere, and Tsamo EtienneInhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plants extracts and plant-derived compoundsRoberto GambariAnticancer Properties of Saffron, Crocus sativus Linn.José-Antonio FernándezLead Compounds and Drug Candýdates from Some Turkýsh Plants for Human HealthÝlkay Orhan, Bilge ÞenerMolecular Design of Multifunctional Anti-Salmonella Agents Based on Natural ProductsIsao Kubo, Ken-ichi Fujita, Ken-ichi Nihei and Aya KuboPlant Growth Inhibitory Activities by Secondary Metabolites Isolated from Latin American Flora Carlos L. Céspedes, Juan C. Marín, Mariana Domínguez, J. Guillermo Avila, Blanca Serrato.Metabolomics – Systematic Studies of the Metabolic ProfilingMahmud Tareq Hassan Khan, Arjumand Ather