Ion Channel Diseases

Edited by

  • Guy Rouleau, GHU Sainte-Justine Research Centre, University of Montreal, Quebec, Canada
  • Claudia Gaspar, Centre of Excellence in Neuromics, CHUM Research Centre, Notre-Dame Hospital Montreal, Quebec, Canada

Ion channel dysfunction in humans leads to impairment of the excitable processes necessary for the normal function of several tissues, such as muscle and brain. It follows that an increasing number of human diseases have been associated with malfunctioning ion channels, many of which have a genetic component. This volume of Advances in Genetics presents a broad and comprehensive overview of the inherited channelopathies in humans, including clinical, genetic and molecular aspects of these conditions. Keeping true to the scope of the serial, novel genomic and modeling research approaches and a review of potential therapeutic approaches for each of these conditions are also incorporated.
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Geneticists, molecular biologists, neurobiologists


Book information

  • Published: December 2008
  • ISBN: 978-0-12-374527-9


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