Intratumor diversity and clonal evolution in cancer

This specialized volume of Advances in Cancer research is dedicated to the complex and largely unexplored field of intratumor diversity, with respect to differences in both genotype and phenotype among cell populations within tumors.

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Advances in Cancer Research

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Hardbound, 368 Pages

Published: September 2011

Imprint: Academic Press

ISBN: 978-0-12-387688-1

1. Introduction
  David Gisselsson
2. Role of telomere dysfunction in genetic intratumour diversity
  Genescà A, Pampalona J, Frías C, Domínguez D, Tusell L
3. How mitotic errors contribute to karyotypic diversity in cancer
  Joshua M Nicholson and Daniela Cimini
4. Nuclear Remodelling as a Mechanism for Genomic Instability in Cancer
  Macoura Gadji,Rhea Vallente, Ludger Klewes, Christiaan Righolt, Landon Wark, Narisorn Kongruttanachok, Hans Knecht, and Sabine Maia
5. Cytogenetic Analysis of Tumor Clonality
  Manuel R. Teixeira, Sverre Heimc
6. Genotyping techniques to address diversity in tumors
  David Lindgren, Mattias Höglund, and Johan Vallon-Christersson
7. Prostate Cancer as a Model System for Genetic Diversity in Tumours
  Jeremy A Squire, Paul C Park, Maisa Yoshimoto, Jennifer Alami, Julia L Williams, Andrew Evans, Anthony M Joshuac
8. Evolutionary mechanisms and diversity in cancer
  Henry H.Q. Heng, Joshua B. Stevens, Steve W. Bremer, Guo Liu, Batoul Y. Abdallah, Christine J. Ye
9. Cancer stem cells in tumor heterogeneity
  Alexander Pietras
10. Cancer: Beyond Speciation
  Mark D. Vincent

Intratumor diversity and clonal evolution in cancer

Contents