Immunology, Inflammation and Diseases of the Eye book cover

Immunology, Inflammation and Diseases of the Eye

This selection of articles from the Encyclopedia of the Eye provides a comprehensive overview of immunological features, diseases and inflammation of the eye and its support structures and organs. Rather than taking an immunological focus that is strictly suitable for clinicians, the volume offers a considerable basic science background and addresses a broad range of topics - the immune system of the eye, its various disorders, mechanisms of inflammation of the eye and visual system, treatment, wound healing mechanisms, stem cells, and more.


Students, researchers and practitioners in ophthalmology and optometry, neuroscience, immunology, physiology, cell biology, pharmacology, and related disciplines

Hardbound, 448 Pages

Published: March 2011

Imprint: Academic Press

ISBN: 978-0-12-381974-1


  • I. Regulation of the Immune Response of the Eye and Its Dysregulation in Inflammation and Infection
    Adaptive Immune System and the Eye: Mucosal Immunity
    Adaptive immune system and the eye: T-cell mediated immunity
    Innate immune system and the eye
    Defense mechanisms of tears and ocular surface
    Role of complement in the ocular immune response
    Immunoregulatory processes that sustain immune privilege in the eye
    Immunosupressive and anti-inflammatory molecules that maintain immune previlege of the eye
    Antigen-presenting cells in the eye and ocular surface
    Regenfus and Cursiefen- Angiogenesis in the eye
    Dry eye: An immune-based inflammation
    Penetrating keratoplasty
    Corneal epithelium- response to infection
    Immunopathogenesis of HSV Keratitis
    Immunopathogenesis of Onchocerciasis (River Blindness)
    Immunopathogenesis of pseudomonas keratitis
    Immunobiology of acanthomeba karatitis
    Pathogenesis of fungal keratitis
    Molecular and cellular mechanisms in allergic conjunctivitis
    Conjunctiva Immune surveillance
    Inflammation of the Conjunctiva
    Immunopathogenesis of experimental uveitic diseases
    Pathogenesis of Uveitis in humans
    Immunobiology of uveal melanoma
    Immunobiology of age-related macular degeneration
    Pathogenesis and Immunology of Bacterial endophthalmitis

    II. Angiogenesis in the Eye and Its Dysfunction in the Retina, Cornea and Vitreous
    Orbiatl vascular anatomy
    Developmental anatomy of retinal and choroidal vasculature
    Development of the retinal vasculature
    Physiological Anatomy of the retinal vasculature
    Physiological anatomy of the choroidal vasculature
    Properties and functions of the vessels of the ciliary body
    Anatomy and regulation of the optic nerve blood flow
    Angiogenesis in response to hypoxia
    Angiogenesis and inflammation
    Angiogenesis in wound healing
    Hemangiogenesis versus lymphangiogenesis
    Innate immunity and angiogenesis
    Mechanisms of Angiostasis
    Stability and functional integrity of new blood vessels
    Vessel regression
    Blood-retinal barrier
    Breakdown of the blood-retinal barrier
    Retinal pigment epithelium barrier
    Breakdown of the retinal pigement epithelium blood-retinal barrier
    Retinal pigment epithelial-choroid interactions
    Macular edema
    Central vein occlusion
    Pathological retinal angiogenesis
    Proliferative vitreoretinopathy
    Choroidal neovascularization
    The vascular stem cell
    Concept of Angiogenic Privilege
    Corneal angiogenesis
    Avascularity of the cornea
    Anti-angiogenic properties of vitreous


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