ICRP Publication 106: Radiation Dose to Patients from Radiopharmaceuticals

A Third Adendum to ICRP Publication 53

By
  • . ICRP

In this report, the Commission provides biokinetic and dosimetric models for 33 radiopharmaceuticals as well as recommendations related to breast-feeding for mothers, who have undergone a nuclear medicine investigation. The report is based on Addenda 3-9 to ICRP Publication 53. Addenda 3-7 have been available on the ICRP web site (www.icrp.org) as interim reports. The work has been carried out in a joint Task Group of ICRP Committees 2 and 3. This Publication provides biokinetic models, absorbed doses and effective doses for the following radiopharmaceuticals: 11C-acetate, 11C-amino acids, 11C-brain receptor substances, 11C-methionine, 18F-amino acids, 18F-FET, 18F-FDG, 111In-monoclonal antibodies/fragments, 123I-fatty acid (BMIPP, IPPA), 123I-monoclonal antibodies/fragments, 131I-monoclonal antibodies/fragments, and 201Tl-ion. The Publication also provides realistic maximum models for 11C and 18F-substances, for which no specific models are available.

Paperback, 140 Pages

Published: February 2009

Imprint: Elsevier

ISBN: 978-0-7020-3450-3

Contents

  • PREFACE

    INTRODUCTION

    SELECTION OF RADIOPHARMACEUTICALS

    SELECTION OF ORGANS AND TISSUES FOR DOSE CALCULATIONS

    BIOKINETIC MODELS AND DATA

    METHODS FOR CALCULATING ABSORBED DOSE

    EFFECTIVE DOSE

    DOSE TO EMBRYO AND FETUS

    REFERENCES, MAIN TEXT

    ANNEX A. SPECIAL BIOKINETIC AND DOSIMETRIC MODELS

    ANNEX B. EXPLANATIONS

    ANNEX C. BIOKINETIC MODELS AND DOSE TABLES

    ANNEX D. RECOMMENDATIONS ON BREAST-FEEDING INTERRUPTIONS

    ANNEX E. RADIATION EXPOSURE OF HANDS IN RADIOPHARMACIES; MONITORING OF THE DOSES AND OPTIMISATION OF PROTECTION

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