Human Genes and Genomes book cover

Human Genes and Genomes

Science, Health, Society

In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences.  The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships.   In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life.  With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in-depth view of the current state of the science and  its relevance across disciplines.

Hardbound, 446 Pages

Published: May 2012

Imprint: Academic Press

ISBN: 978-0-12-385212-0


  • ". . . a beautifully written and insightful genetics book that hits all the right notes. Major principles are illustrated in the context of real disease, both Mendelian and complex, which keeps the relevance high."

    Michael J. Dougherty, PhD, Director of Education, American Society of Human Genetics

    "This thoughtful and scholarly book, teaching about common traits and rare inherited disorders, is beautifully written and accessible to science students and non-science students alike."

    Margretta Seashore, MD, Director, Genetic Consultation Service and Director, Biochemical Disease Detection Laboratory, Department of Laboratory Medicine, Yale University School of Medicine

    "A master story teller and one of the founders of the field, Rosenberg tells the story of human genetics as few others can - anchored in history but with a fresh eye towards what the study of the human genome teaches us about genes and their importance for both biology and medicine."

    Huntington F. Willard, PhD, Director, Duke Institute for Genome Sciences & Policy, Duke University


  • Foreword
    Framing the Field
    Introducing the CORE CONCEPTS
    Growth, Development, and Reproduction
    Transmission of Genes
    Structure of Genes, Chromosomes, and Genomes
    Expression of Genes and Genomes
    Biological Evolution
    Human Individuality
    Chromosome Abnormalities
    Single-Gene Defects
    Multifactorial Traits
    Disorders of Variable Genomic Architecture
    Birth Defects
    The Genetics of Cancer
    Detection and Treatment of Genetic Disorders
    Population and Evolutionary Genetics
    Personalized Genetics and Genomics
    Additional Reading
    Answers to Review Questions


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