Human Chorionic Gonadotropin (hGC)

INTRODUCTION

 Chapter 1: THE EXPANDING WORLD OF hCG

Robert Hussa

Chapter 2: HISTORY AND INTRODUCTION TO HUMAN CHORIONIC GONADOTROPIN (hCG): ONE NAME FOR AT LEAST THREE INDEPENDENT MOLECULES
Laurence Cole

Chapter 3: INTRODUCTION TO PREGNANCY IMPLANTATION, VILLOUS FORMATION, AND HEMOCHORIAL PLACENTATION
Laurence Cole

 GENETICS, SYNTHESIS, SECRETION, STRUCTURE, AND DEGRADATION OF hCG

Chapter 4: THE MOLECULAR GENETICS OF hCG
Stephen Butler

Chapter 5: STRUCTURE, SYNTHESIS, SECRETION, AND FUNCTION OF hCG
Laurence Cole, PhD and Stephen Butler

Chapter 6: COMPARISSON OF STRUCTURES OF hCG AND HYPERGLYCOSYLATED hCG
Laurence Cole

Chapter 7: STRUCTURES OF FREE a-SUBUNIT AND FREE ß-SUBUNIT
Laurence Cole

Chapter 8: GLYCOBIOLOGY OF hCG
Akira Kobata

Chapter 9: DEGRADATION PRODUCTS OF hCG, HYPERGLYCOSYLATED hCG, AND FREE ß-SUBUNIT
Laurence Cole

Chapter 10: THE THREE DIMENSIONAL STRUCTURE OF hCG
Laurence Cole

BIOLOGICAL FUNCTION OF hCG

Chapter 11: PARADIGM SHIFT ON THE TARGETS OF hCG ACTIONS

CV Rao

Chapter 12: THE hCG RECEPTOR

Laurence Cole and Stephen Butler

Chapter 13: BIOLOGICAL FUNCTIONS OF HYPERGLCOSYLATED hCG
Laurence Cole

Chapter 14: BIOLOGICAL FUNCTION OF THE FREE BETA SUBUNIT: EXPRESSION AND TREATMENT TARGET IN CANCER

Steven Butler and Ray Iles

CLINICAL APPLICATIONS

Chapter 15: USE OF hCG IN REPRODUCTIVE DYSFUNCTION
Cisco Byrn

Chapter 16: hCG IN THE IVF CLINIC
Ervin Jones,

Chapter 17: ILLICIT USE OF hCG IN DIETARY PROGRAMS AND USE TO PROMOTE ANABOLISM
Laurence Cole

hCG TESTS

Chapter 18: ANTIBODYS FOR INTACT hCG, TOTAL hCG, FREE SUBUNITS, GLYCOSYLATION VARIANTS, AND hCG FRAGMENTS
Laurence Cole

Chapter 19: QUANTITATIVE hCG ASSAYS
Laurence Cole

Chapter 20: FALSE-POSITIVE hCG ASSAYS
Laurence Cole

Chapter 21: SPECIFICITY OF DIFFERENT hCG ASSAYS
Laurence Cole

Chapter 22: POINT-OF-CARE PREGNANCY TESTS
Laurence Cole

Chapter 23: OVER-THE-COUNTER PREGANCY TESTS
Laurence Cole

Chapter 24: hCG STANDARDS
Ulf Stenman

TEST APPLICATIONS

Chapter 25: BACKGROUND hCG
Laurence Cole

Chapter 26: PREGNANCY TESTING
Laurence Cole

Chapter 27: PREDICTING SPONTANEOUSLY ABORTED (SAB) PREGNANCIES
Laurence Cole

Chapter 28: hCG, HYPERGLYCOSYLATED hCG, AND FREE ß-SUBUNIT IN PREDICTING DOWN SYNDROME PREGNANCIES AND PREECLAMPSIA
Laurence Cole

Chapter 29: hCG IN MONITORING GESTATIONAL TROPHOBLASTIC DISEASES

Laurence Cole

Chapter 30: USE OF HYPERGLYCOSYLATED hCG AS A UNIQUE MARKER OF GESTATIONAL TROPHOBLASTIC NEOPLASMS

Laurence Cole and Carolyn Muller

Chapter 31: PITUITARY hCG AND FAMILIAL hCG
Laurence Cole

Chapter 32: hCG, FREE ß-SUBUNIT AND ß-CORE FRAGMENT AS MARKERS OF MALIGNANCIES
Laurence Cole

BASIC METHODS

Chapter 33: hCG AND HYPERGLYCOSYLATED HCG PURIFICATION FROM SERUM, URINE, AND CULTURE FLUIDS

Laurence Cole

Chapter 34: DISSOCIATION, DESIALYLATION, AND CLEAVAGE OF HCG

Laurence Cole

Chapter 35: hCG AND FREE ß-SUBUNIT PRODUCING CELL LINES

Laurence Cole

EVOLUTION, SUMMARY AND THE FUTURE

Chapter 36: EVOLUTION OF hCG, EVOLUTION OF HUMANS, EVOLUTION OF HUMAN PREGNANCY DISORDERS AND CANCER
Laurence Cole

Chapter 37: SUMMARY: hCG A REMARKABLE MOLECULE
Laurence Cole

Chapter 38: hCG AND THE FUTURE
Laurence Cole