Host Response to Biomaterials book cover

Host Response to Biomaterials

The Impact of Host Response on Biomaterial Selection

Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response.

The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions.

Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine.

Biomedical engineers, Biomaterials scientists, Medical device developers, undergraduate and graduate level students in biomedical engineering, bioengineering, and materials science programs

Hardbound, 460 Pages

Published: May 2015

Imprint: Academic Press

ISBN: 978-0-12-800196-7


  • Foreword
    1. Overview of components (variables) that determine the host response to implanted biomaterials
    2. Perspectives on the inflammatory healing, and foreign body response to biomaterials and medical devices
    3. The concept of biocompatibility and the relationship of biomaterial composition to the expected host response
    4. Host Response to naturally occurring biomaterials
    5. Molecular events at tissue-biomaterial interface
    6. The innate immune response and its role in response to biomaterials. Focus upon macrophage and macrophage phenotype
    7. Role of dendritic cells in response to biomaterials
    8. The acquired immune system response to biomaterials, including both naturally occurring and synthetic biomaterials
    9. Fibrotic response to biomaterials and all associated sequence of fibrosis
    10. Human anti-Gal and anti-non gal immune response to biologic tissue implants
    11. Effect of aging on the host response to biomaterials
    12. Host Response to orthopedic implants (metals & plastics)
    13. Host Response to surgical mesh materials used for pelvic floor reconstruction
    14. Methods used to evaluate the host responses


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