HIV: Molecular Biology and Pathogenesis: Viral Mechanisms, 48

  • J. August, John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.
    • Ferid Murad, University of Texas Medical School, Houston, U.S.A.
      • Kuan-Teh Jeang, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, U.S.A.


      Graduate students, postdoctoral fellows, and senior researchers in virology and pharmacology, as well as clinicians and clinical fellows in infectious diseases.


Book information

  • Published: August 2000
  • ISBN: 978-0-12-032949-6


"Recommended not only to pharmacologists but also to all those in related disciplines."
Praise for the Serial, --NATURE

"Superb reading material."
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
--H.E. Kaufmann in CHEMOTHERAPY

Table of Contents

HIV RNA Packaging and Lentivirus-Based Vectors, A.M.L. Lever.Multiple Biological Roles Associated with the Repeat (R) Region of the HIV-1 RNA Genome, B. Berkhout.HIV Accessory Proteins: Multifunctional Components of a Complex System, S. Bour and K. Strebel.Role of Chromatin in HIV-1 Transcriptional Regulation, C. Van Lint.NF-kB and HIV: Linking Viral and Immune Activation, A.B. Rabson and H.-C. Lin.Tat as a Transcriptional Activator and a Potential Therapeutic Target for HIV-1, A. Gatignol and K.-T. Jeang.From the Outside In: Extracellular Activities of HIV Tat, D. Noonan and A. Albini.Rev Protein and Its Cellular Partners, J. Kjems and P. Askjaer.HIV-1 Nef: A Critical Factor in Viral-Induced Pathogenesis, A.L. Greenway, G. Holloway, and D.A. McPhee.Nucleocapsid Protein of Human Immunodeficiency Virus as a Model Protein with Chaperoning Functions and as a Target for Antiviral Drugs, J.-L. Darlix, G. Cristofari, M. Rau, C. Pechoux, L. Berthoux, and B. Roques.Bioactive CD4 Ligands as Pre- and/or Postbinding Inhibitors of HIV-1, L. Briant and C. Devaux.