HIV I: Molecular Biology and Pathogenesis: Clinical Applications

Edited by

  • Kuan-Teh Jeang, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, U.S.A.

Series Editor:

  • J. August, John Hopkins University; Department of Pharmacology, Baltimore, Maryland, U.S.A.
  • Ferid Murad, University of Texas Medical School, Houston, U.S.A.

Although it is one of the most-widely studied viruses, many mysteries still remain about HIV. Covering the latest advances and challenges associated with clinical application of new antiviral drugs and vaccines, this revised edition is a companion to Murad:HIV-1: Molecular Biology and Pathogenesis, 2E. Leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus.
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Graduate students, postdoctoral fellows, and senior researchers in virology and pharmacology, as well as clinicians and clinical fellows in infectious diseases


Book information

  • Published: December 2007
  • ISBN: 978-0-12-373601-7

Table of Contents

HIV Therapeutics: Past, Present, and FutureHIV Drug Resistance and Viral Fitness Inhibitors of HIV-1 Reverse Transcriptase HIV-I Protease: Maturation, Enzyme Specificity, and Drug ResistanceHIV-I Integrase Inhibitors: Past, Present, and Future Selection of HIV Replication Inhibitors: Chemistry and BiologyMaturation or assembly inhibitor compounds against HIV-1HIV-I Gene Therapy: Promise for the Future Assessment of HIV Vaccine Development: Past, Present, and Future CTL immunity approaches for HIV-1 vaccineshumoral immunity approaches for HIV-1 vaccines.HIV-I-Associated Central Nervous System DysfunctionMolecular Mechanisms of Human Immunodeficiency Virus Type I Mother-Infact TransmissionMolecular Epidemiology of HIV-I: An Example of Asia Simian Immunodeficiency Virus Infection of Monkeys as a Model System for the Study of AIDS Pathogenesis, Treatment and PreventionAnimal Models for AIDS Pathogenesis SCID-hu mouse models for studying HIV-AIDS and for drug testing.