Histopathology of Preclinical Toxicity Studies
Interpretation and Relevance in Drug Safety Evaluation
Clinical toxicologists, pathologists, and pharmacologists involved professionally in drug safety evaluation and especially those researchers working in pharmaceutical companies, contract laboratories and in government agencies.
Hardbound, 892 Pages
Published: November 2011
Imprint: Academic Press
"There are several books on the subjects of rodent pathology, toxicologic pathology, and toxicology and several veterinary and toxicologic pathology journals but nothing like this fourth edition of Peter Greavesâs treatise. It reads like a Greaves Tox Path Wiki or perhaps a Greavipedia on preclinical histopathology and toxicology. His progressive editions since 1991 have increased in thickness and weight, adding more information and thousands of references. A Kindle edition is available with links to references in the reference lists. His experience as a physician pathologist working on drug research and development, animal toxicity, and carcinogenicity studies is clearly demonstrated in this comprehensive textâ¦. this fourth edition can be extremely helpful if you are a veterinary or medical pathologist working with research and development and safety assessment of chemicals, particularly drugs. I highly recommend it for that audience and for toxicologists, other scientists, and regulators working with drug and other chemical safety. It is a must-have reference book in this field."--Veterinary Pathology Online "This is an excellent and very relevant textbook for all new and practicing toxicologists and indeed, anyone involved in generating, interpreting, or reviewing toxicology data. I would thoroughly recommend having a copy."--British Toxicology Society Newsletter "Greaves (cancer studies and molecular medicine, U. of Leicester, UK) supplies pathologists, toxicologists, and pharmacologists involved in drug- safety evaluation in corporate, government, academic, and research settings with a text on drug-induced pathology in laboratory animals and the relevance of animal findings for human patients,including comparative anatomy and pathology and drug-induced reactions in patients. Chapters are organized by body system and describe specific pathologies in them. This edition is in full color and contains updated content on the commonly used transgenic animal models used in safety assessment, specific tumor types induced by drugs in rodents, and new drug-induced pathologies and lesions. Academic Press is an imprint of Elsevier."--Reference and Research Book News, October 2012