Hematopathology book cover

Hematopathology

A Volume in the High Yield Pathology Series (Expert Consult - Online and Print)

Recognize the classic look of hematologic diseases and quickly confirm your diagnoses with Hematopathology: A Volume in the High Yield Pathology Series. A templated format, excellent color photographs, authoritative content, and online access make this an ideal reference for busy pathologists.

Hardbound, 320 Pages

Published: June 2013

Imprint: Saunders

ISBN: 978-1-4377-1758-7

Reviews

  • "**Features**

    Among the numerous features that set this apart from many of the other quick references for hematopathology is the expansive benign section that includes reactive lymphadenopathies, reactive histiocytic disorders, and red cell disorders. Each topic is covered in just 1-to-2 pages with clinical features, histological findings, differential diagnosis, and correlating ancillary testing (i.e. immunopathology, molecular testing, and hemoglobin electrophoresis). In addition to the top-quality images and easy-to-follow bulleted text, the book includes access to the Expert Consult website.

    **Assessment**

    This is a great addition to the High-Yield Pathology series. With high-quality images, a broad spectrum of benign and malignant hematologic conditions, information on ancillary testing, and an easy-to-follow layout makes this a perfect quick reference for busy pathologists." - Jamie Boone, D.O.(University of Kansas Medical Center) Doody 4 star rating!

    "Hematopathology...comes from the the 'High Yield Pathology' series. As such. it's style is very much a bullet-point list of key facts and information, alongside numerous high quality cytological and histological photographs, and printed on glossy good quality paper stock... This book is a useful overview for confirming suspected diagnoses, and to help guide further testing."

    HaemTrainee, January 2014


Contents

  • I. INHERITED RED CELL DISORDERS

    A. Thalassemias

    Alpha-Thalassemia

    Beta-Thalassemia

    B. Hemoglobinopathies

    Sickle Cell Disease

    Hemoglobin C Disease

    Hemoglobin E Disease

    Heinz Body Hemolytic Anemia

    C. Enzyme Defects

    Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency

    Pyruvate Kinase Deficiency

    D. Disorders of Heme Synthesis

    Sideroblastic Anemia (Congenital and Acquired)

    E. Red Cell Membrane Disorders

    Hereditary Spherocytosis

    Hereditary Elliptocytosis (HE) and Related Disorders

    F. Other Congenital Red Cell Disorders

    Congenital Dyserythropoietic Anemia (CDA)

    II. ACQUIRED RED CELL DISORDERS

    A. Red Cell Membrane Disorders

    Paroxysmal Nocturnal Hemoglobinuria (PNH)

    B. Nutritional Deficiencies

    Iron Deficiency Anemia (IDA)

    Folate and B12 (Cobalamin) Deficiency

    C. Toxins

    Lead Toxicity

    Hematologic Complications of Alcoholism

    D. Intravascular Hemolysis

    Traumatic Hemolysis

    E. Immunologic Destruction

    Autoimmune Hemolytic Anemia (AIHA)

    F. Myelophthisic Anemias

    Metastatic Lesions in Bone Marrow Biopsies

    Gaucher Disease

    Storage Disorders: Niemann-Pick Disease (NPD)

    G. Red Cell Aplasias

    Red Cell Aplasia

    Parvovirus Infection

    III. INHERITED WHITE CELL AND PLATELET DISORDERS

    Chediak-Higashi Syndrome

    Gray Platelet Syndrome

    May-Hegglin Anomaly

    Pelger-Huet Anomaly

    IV. INFECTIOUS DISORDERS SEEN IN BLOOD

    Malaria

    Babesiosis

    Ehrlichiosis/Anaplasmosis

    African Trypanosomiasis

    Chagas Disease

    V. DISORDERS OF HEMOSTASIS

    Disseminated Intravascular Coagulation (DIC)

    Thrombotic Thrombocytopenia Purpura (TTP)/Hemolytic Uremic Syndrome (HUS)

    VI. BONE MARROW FAILURE SYNDROMES

    Aplastic Anemia

    VII. REACTIVE LYMPHADENOPATHIES

    A. Infections

    Tuberculosis and Mycobacterial Lymphadenopathy

    Cryptococcus Lymphadenitis

    Histoplasmosis

    Candidiasis

    Infectious Mononucleosis

    Cytomegalovirus (CMV) Infection

    Herpes Simplex Virus (HSV) Lymphadenitis

    Toxoplasmosis

    Syphilitic Lymphadenitis

    B. Non-Infectious

    Sarcoidosis

    Systemic Lupus Erythematosus (SLE) Lymphadenopathy

    Rheumatoid Lymphadenopathy

    Castleman Disease

    a. Hyaline Vascular Variant

    b. Multicentric/Plasma Cell Variant

    Foreign Body Lymphadenopathy

    Dermatopathic Lymphadenopathy

    Non-Specific Lymphadenopathy

    VIII. REACTIVE HISTIOCYTIC DISORDERS

    Rosai-Dorfman Disease

    Erdheim-Chester Disease

    Hemophagocytic Lymphohistiocytosis (Primary and Acquired)

    IX. LYMPHOID NEOPLASMS

    A. Lymphoblastic Neoplasms

    B Lymphoblastic Leukemia/Lymphoma (B-ALL/LBL)

    T Lymphoblastic Leukemia/Lymphoma (T-ALL/LBL)

    B. Mature B-Cell Neoplasms

    Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

    B-Cell Prolymphocytic Leukemia

    Hairy Cell Leukemia

    Hairy Cell Leukemia---Variant

    Splenic Marginal Zone Lymphoma

    Extranodal Marginal Zone Lymphoma

    A. Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT Lymphoma)

    B. Cutaneous Marginal Zone Lymphoma

    Nodal Marginal Zone Lymphoma

    Lymphoplasmacytic Lymphoma

    Mantle Cell Lymphoma

    Follicular Lymphoma

    Primary Cutaneous Follicle Center Lymphoma

    Burkitt Lymphoma (BL)

    Diffuse Large B-Cell Lymphoma (DLBCL), Not Otherwise Specified (Including with Chronic Inflammation)

    B-Cell Lymphoma, Unclassifiable, With Features Intermediate between Diffuse Large B-Cell Lymphoma (DLBCL) and Burkitt Lymphoma

    T-Cell/Histiocytic-Rich Large B-Cell Lymphoma

    B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Classical Hodgkin Lymphoma (CHL)

    Primary Diffuse Large B-Cell Lymphoma (DLBCL) of the CNS

    Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type

    EBV-Positive Diffuse Laarge B-Cell Lymphoma (DLBCL) in the Elderly

    Lymphomatoid Granulomatosis

    Primary Mediastinal Large B-Cell Lymphoma (PMBCL)

    Intravascular Lymphoma

    Plasmablastic Lymphoma

    Large B-Cell Lymphoma Arising in HHV-8-Associated Multicentric Castleman Disease (MCD)

    Primary Effusion Lymphoma and Related Entities

    ALK+ Large B-Cell Lymphoma

    C. Plasma Cell Neoplasms

    Monoclonal Gammopathy of Undetermined Significance

    Plasma Cell Myeloma

    Plasmacytoma

    Immunoglobulin Deposition Diseases

    Osteosclerotic Myeloma

    D. Mature T-Cell and NK-Cell Neoplasms

    Mycosis Fungoides

    Sézary Syndrome

    Primary Cutaneous CD30+ T-Cell Lymphoproliferative Disorders

    1. Lymphomatoid Papulosis (LYP)
    2. Primary Cutaneous Anaplastic Large Cell Lymphoma (ALCL)

    Primary Cutaneous Gamma-Delta T-Cell Lymphoma

    Primary Cutaneous CD8+ Aggressive Epidermotropic Cytotoxic T-Cell Lymphoma

    Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoma

    T-Cell Prolymphocytic Leukemia

    T-Cell Large Granular Lymphocytic Leukemia (T-LGL)

    Peripheral T-Cell Lymphoma, Not Otherwise Specified

    Angioimmunoblastic T-Cell Lymphoma

    Anaplastic Large Cell Lymphoma, ALK+

    Anaplastic Large Cell Lymphoma, ALK-

    EBV-Positive T-Cell Lymphoproliferative Disorders of Childhood

    1. Systemic EBV-Positive T-Cell Lymphoproliferative Disease of Childhood
    2. Hydroa Vacciniforme-Like Lymphoma

    Adult T-Cell Leukemia/Lymphoma (ATLL)

    Enteropathy-Associated T-Cell Lymphoma (EATL)

    Hepatosplenic T-Cell Lymphoma

    Subcutaneous Panniculitis-Like T-Cell Lymphoma

    E. NK-Cell Neoplasms

    Extranodal NK/T-Cell Lymphoma

    Aggressive NK-Cell Leukemia

    Chronic Lymphoproliferative Disorder of NK Cells

    F. Classical Hodgkin Lymphoma

    Nodular Sclerosis Type

    Mixed Cellularity Type

    Lymphocyte-Rich Type

    Lymphocyte-Depleted Type

    Nodular Lymphocyte-Predominant Hodgkin Lymphoma

    X. IMMUNODEFICIENCY-ASSOCIATED LYMPHOPROLIFERATIVE DISORDERS

    A. HIV-Associated Lymphoproliferative Disorders

    HIV Lymphadenitis

    HIV-Associated Lymphoproliferative Disorders

    B. Post-Transplant Lymphoproliferative Disorders (PTLDs)

    Early, Polymorphic, Monomorphic, and Hodgkin Types

    C. Primary Immunodeficiency-Associated Lymphoproliferative Disorders

    Overview of Primary Immunodeficiency-Associated Lymphoproliferative Disorders

    Autoimmune Lymphoproliferative Syndrome (ALPS)

    XI. MYELOID NEOPLASMS

    A. Myeloproliferative Disorders

    Chronic Myelogenous Leukemia (CML)

    Chronic Neutrophilic Leukemia (CNL)

    Polycythemia Vera (PV)

    Essential Thrombocythemia (ET)

    Primary Myelofibrosis (PMF)

    Chronic Eosinophilic Leukemia (CEL)

    Mastocytosis

    B. Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of PDGFRA, PDGFRB, or FGFR1

    C. Myelodysplastic/Myeloproliferative Neoplasms

    Chronic Myelomonocytic Leukemia

    Atypical Chronic Myeloid Leukemia

    Juvenile Myelomonocytic Leukemia (JMML)

    D. Myelodysplastic Syndromes

    Refractory Anemia with Unilineage Dysplasia

    Refractory Anemia with Ring Sideroblasts

    Refractory Cytopenia with Multilineage Dysplasia

    Refractory Anemia with Excess Blasts (RAEB)

    Myelodysplastic Syndrome (MDS) with Isolated del(5q)

    E. Acute Myeloid Leukemia with Recurrent Genetic Aberrations

    AML with t(8;21)(q22;q22); RUNX1/RUNX1T1

    Acute Myeloid Leukemia (AML) with inv (16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11

    Acute Promyelocytic Leukemia with t(15;17)(q22;q12); PML-RARA

    Acute Myeloid Leukemia (AML) with t(9;11)(p22;q23); MLLT3-MLL

    Acute Myeloid Leukemia (AML) with t(6;9)(p23;q34); DEK-NUP214

    Acute Myeloid Leukemia with (AML) inv(3)(q21q26.6) or t(3;3)(q21;q26.2);RPN1-EVI1

    Acute Myeloid Leukemia (AML) (Megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1

    Acute Myeloid Leukemia (AML) with Mutated NPM1

    Acute Myeloid Leukemia (AML) with Mutated CEBPA

    F. Acute Myeloid Leukemia, Not Otherwise Specified

    AML with Minimal Differentiation

    Acute Myeloid Leukemia (AML) without Maturation

    Acute Myeloid Leukemia (AML) with Maturation

    Acute Myelomonocytic Leukemia

    Acute Monoblastic Leukemia

    Acute Monocytic Leukemia

    Acute Erythroid Leukemia, Erythroid/Myeloid Subtype

    Acute Erythroid Leukemia, Pure Erythroid Leukemia Subtype

    Acute Megakaryoblastic Leukemia

    G. Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes

    H. Therapy-Related Myeloid Neoplasms

    I. Myeloid Sarcoma

    J. Myeloid Proliferations Related to Down Syndrome (DS)

    K. Blastic Plasmacytoid Dendritic Cell Neoplasm

    XII. HISTIOCYTIC AND DENDRITIC CELL NEOPLASMS

    Histiocytic Sarcoma

    Langerhans Cell Histiocytosis

    Langerhans Cell Sarcoma

    Follicular Dendritic Cell Sarcoma

    Interdigitating Dendritic Cell Sarcoma

    Indeterminate Dendritic Cell Tumor

    Fibroblastic Reticular Cell Tumor

    XIII. THYMOMA AND THYMIC CARCINOMA

    Thymoma

    Thymic Carcinoma

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