Hematology book cover


Clinical Principles and Applications

Featuring hundreds of full-color photomicrographs, Hematology: Clinical Principles and Applications prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells.

Book, 864 Pages

Published: January 2011

Imprint: Saunders

ISBN: 978-1-4557-3665-2


  • Part I: Introduction to Hematology
    1. An Overview of Clinical Laboratory Hematology
    2. Safety in the Hematology Laboratory
    3. Specimen Collection
    4. Care and Use of the Microscope
    5. Quality Assurance in Hematology and Hemostasis Testing
    Part II: Hematopoiesis and Blood Cell Physiology
    6. Cellular Structure and Function
    7. Hematopoiesis
    8. Erythrocyte Production and Destruction
    9. Energy Metabolism and Membrane Physiology of the Erythrocyte
    10. Hemoglobin Metabolism
    11. Iron Metabolism
    12. Leukocyte Development, Kinetics, and Function
    13. Platelet Production, Structure, and Function
    Part III: Routine Laboratory Evaluation of Blood Cells
    14. Routine and Point of Care Testing in Hematology: Manual and Semi-Automated Methods
    15. Examination of the Peripheral Blood Film and Correlation with the Complete Blood Count
    16. Bone Marrow Collection and Examination
    17. Hematologic Body Fluid Examination
    Part IV: Hematopathology: Erythrocyte Disorders
    18. Anemias: Red Blood Cell Morphology and Approach to Diagnosis
    19. Disorders of Iron and Heme Metabolism
    20. Anemias Caused by Defects of DNA Metabolism
    21. Bone Marrow Failure
    22. Introduction to Increased Erythrocyte Destruction
    23. Intrinsic Defects Leading to Increased Erythrocyte Destruction
    24. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Nonimmune Causes
    25. Extrinsic Defects Leading to Increased Erythrocyte Destruction-- Immune Causes
    26. Hemoglobinopathies: Structural Hemoglobin Defects
    27. Thalassemias: Quantitative Hemoglobin Defects
    Part V: Leukocyte Disorders
    28. Non-Malignant Leukocyte Disorders
    29. Introduction to Leukocyte Neoplasms
    30. Cytochemistry
    31. Cytogenetics
    32. Molecular Diagnostics in the Hematology Laboratory
    33. Flow Cytometric Analysis of Hematologic Disorders
    34. Myeloproliferative Disorders
    35. Myelodysplastic Syndromes
    36. Acute Leukemias
    37. Lymphomas and Chronic Lymphocytic Leukemias
    Part VI: Hematology in Selected Populations
    38. Pediatric and Geriatric Hematology
    Part VII: Cell Counting Automation
    39. Automated Cell Counting Instrumentation
    Part VIII: Hemostasis and Thrombosis
    40. Normal Hemostasis and Coagulation
    41. Hemorrhagic Coagulation Disorders
    42. Thrombosis Risk Testing
    43. Thrombocytopenia and Thrombocytosis
    44. Qualitative Disorders of Platelets and Vasculature
    45. Laboratory Evaluation of Hemostasis
    46. Monitoring Anticoagulant Therapy
    47. Coagulation Instrumentation


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